LDL

Alpinumisoflavone has atheroprotective effects, may result from their ability to upregulate mechanisms promoting HDL-cholesterol and …

Taurine (2-Aminoethanesulfonic acid), an organic acid, is distributed in various animal tissues.

Carvedilol phosphate hemihydrate (BM 14190 phosphate hemihydrate) is the phosphate salt form of carvedilol, a …

Isosalvianolic acid C exhibits more potent activity than probucol except for salvianolic acid F .

Imanixil (HOE-402 free base) is an LDL receptor (LDLR) inducer, a hypolipidemic and hypocholesterolemic compound …

Erycibelline has antiobesity activity, it may be a useful therapeutic agent for body weight control …

Trichosanatine and squamosamide, as potential candidates as lead compounds for further study in drug development …

Levosemotiadil(SA 3212) is a novel calcium antagonist and a very potent inhibitor of low-density lipoprotein …

7beta-Hydroxycholesterol, a major cytotoxin in oxidized LDL, induces Ca(2+) oscillations, MAP kinase activation and apoptosis …

Cleomiscosin C has antioxidant activity, it protects against the oxidative modification of apoB-100 induced by …

BIBB 515 is a selective and potent inhibitor of OSC in vivo with an ED50 …

Gardenin A shows neurotrophic effects via activating MAPK/ERK, PKC, and PKA. Gardenin A exhibits antidepressant, …

Tanshindiol C protects macrophages from oxLDL induced foam cell formation via activation of Prdx1/ABCA1 signaling …

Ligupurpuroside B has antioxidant activity.

Stachybotramide preferentially stimulate the plasma cholesteryl ester transfer protein (CETP)-mediated transfer of cholesteryl esters (CE) …

Atorvastatin Sodium (Lipitor) is a competitive inhibitor of HMG-CoA reductase and increases the expression of …

Cleomiscosin A is derived from Acer okamotoanum leaf and twig and shows inhibitory activity to …

beta-Amyrin acetate inhibits HMG-CoA Reductase (HMGCR) and sEH activity with IC50 of 3.4 μM. beta-Amyrin …

Ligupurpuroside A has antioxidant,and hypolipidemic effects, it can significantly inhibit lipid accumulation in HepG2 cell …

3'-Demethylnobiletin has chemopreventive effects on colon carcinogenesis, it can significantly inhibit the growth of human …

Flavone glycoside from Robinia with antibacterial and diuretic properties; derived from kaempferol.The ability of robinin …

Kudinoside D exerts anti-adipogenic effects through modulation of adipogenic transcription factors via AMPK signaling pathway.

Euscaphic acid has anti-diabetic, and anti-inflammatory activities, it inhibits LPS-induced inflammatory responses by interference with …

T0901317 is a potent and selective agonist for both LXR and FXR, with EC50 of …

Procyanidin A1 (Proanthocyanidin A1) has antiallergic effects, it inhibits degranulation downstream of protein kinase C …

Siamenoside I is a natural product,and is one of the mogrosides that has several kinds …

Probucol is an anti-hyperlipidemic drug initially developed in the treatment of coronary artery disease by …

SBC-115076 is a potent extracellular proprotein convertase subtilisin kexin type 9 (PCSK9) antagonist.

1,2,3,6-Tetragalloylglucose (TeGG) has antioxidative activity, it also shows the most potent anticomplement activity (IC50 = …