Cysteinprotease
Cysteinprotease-Inhibitoren sind Verbindungen, die Cysteinproteasen hemmen, eine Klasse von Enzymen, die Proteine durch das Spalten von Peptidbindungen abbauen, bei denen ein Cysteinrest als Nukleophil fungiert. Diese Enzyme sind an verschiedenen physiologischen Prozessen beteiligt, darunter Apoptose, Immunantwort und Proteinabbau. Cysteinprotease-Inhibitoren sind entscheidend für das Studium von Krankheiten wie Krebs, neurodegenerativen Störungen und parasitären Infektionen. Bei CymitQuimica bieten wir Cysteinprotease-Inhibitoren an, um Ihre Forschung in den Bereichen Proteolyse, Zellregulation und Wirkstoffentwicklung zu unterstützen.
96 Produkte aus dem Bereich "Cysteinprotease" gefunden
Sortieren nach
Reinheit (%)
0
100
|
0
|
50
|
90
|
95
|
100
Cathepsin L-IN-3
CAS:<p>Cathepsin L-IN-3, a tripeptide-sized inhibitor of cathepsin L, effectively targets this specific enzyme.</p>Formel:C41H49N7O4SFarbe und Form:SolidMolekulargewicht:735.94Z-Leu-Tyr-Chloromethylketone
CAS:<p>Z-Leu-Tyr-Chloromethylketone is a calpain inhibitor [1].</p>Formel:C24H29ClN2O5Farbe und Form:SolidMolekulargewicht:460.95Z-Arg-Arg-βNA acetate
CAS:<p>Z-Arg-Arg-βNA acetate serves as a sensitive dipeptide substrate for Cathepsin B protease, while demonstrating resistance to proteases H and L. This compound is crucial for differentiating non-Cathepsin B type proteins.</p>Formel:C32H43N9O6Farbe und Form:SolidMolekulargewicht:649.74Cathepsin D and E FRET Substrate acetate(839730-93-7 Free base)
<p>Fluorogenic substrate for cathepsins D & E; cleaves at Phe-Phe bond; not for B, H, L. Useful for assays and studies.</p>Farbe und Form:Odour SolidGallinamide A TFA
CAS:<p>Gallinamide A TFA is a peptide that exhibits linear deposition and serves as a potent inhibitor of cathepsin L (CatL) with an IC50 of 17.6 pM. It inhibits SARS-CoV-2 infection by targeting CatL (EC50: 28 nM) and also inhibits Plasmodium falciparum with an IC50 of 50 nM [1] [2].</p>Formel:C33H53F3N4O9Farbe und Form:SolidMolekulargewicht:706.79Protease Inhibitor Library
<p>A unique collection of 343 protease and proteasome inhibitors for research in chemical genomics, and drug screening;</p>Farbe und Form:Odour SolidCathepsin D and E FRET Substrate
CAS:<p>Mca-GKPILFFRL-Dpa-r-amide, FRET substrate for cathepsin D and E. Also cleaved by napsin A.</p>Formel:C85H122N22O19Farbe und Form:SolidMolekulargewicht:1756.046Hepcidin-1 (mouse)
CAS:<p>Hepcidin-1 (mouse) is a peptide hormone that regulates iron balance, elevates mRNA for TRAP, cathepsin K, and MMP-9, and promotes TRAP-5b protein secretion.</p>Formel:C111H169N31O35S8Farbe und Form:SolidMolekulargewicht:2754.24N-CBZ-Phe-Arg-AMC
CAS:<p>Z-FR-AMC substrate for serine proteases; cathepsins, kallikrein, plasmin. Substrate: 330/390 nm; Product: 342/441 nm.</p>Formel:C33H36N6O6Reinheit:98%Farbe und Form:White To Off-White PowderMolekulargewicht:612.68FGA139
<p>FGA139 is an inhibitor of cysteine proteases, specifically targeting cathepsin B and L with IC50 values of 4.98 μM and 3.14 μM, respectively. It reduces the production of NO in LPS-induced RAW264.7 cells and lowers TNFα levels in microglia, demonstrating antioxidant and anti-inflammatory properties. Additionally, FGA139 enhances the secretion of neuroprotective metabolites such as purines and linoleic acid in LPS-stimulated microglia. This compound is applicable in the study of neuroinflammatory diseases.</p>Formel:C48H58BF2N7O5Farbe und Form:SolidMolekulargewicht:861.45605Relacatib
CAS:<p>Relacatib (SB-462795) is a potent cathepsins K, L, V inhibitor with high affinity (Ki: 41-68 pM) and reduces bone resorption effectively.</p>Formel:C27H32N4O6SFarbe und Form:SolidMolekulargewicht:540.64Z-FG-NHO-Bz
CAS:<p>Z-FG-NHO-Bz is a selective inhibitor of cathepsin [1].</p>Formel:C26H25N3O6Farbe und Form:SolidMolekulargewicht:475.49Cathepsin C-IN-6
<p>Cathepsin C-IN-6 (compound 2), an E-64c-hydrazideas-derived inhibitor of cathepsin C, possesses anti-inflammatory properties and impedes neutrophil elastase</p>Formel:C24H35N5O4·xC2HF3O2Farbe und Form:SolidLeupeptin
CAS:<p>Leupeptin, from actinomycetes, inhibits various proteases (e.g., trypsin, plasmin, kallikrein, papain, cathepsin B) but not α-chymotrypsin/thrombin.</p>Formel:C20H38N6O4Reinheit:98%Farbe und Form:SolidMolekulargewicht:426.562N-CBZ-Phe-Arg-AMC TFA
<p>N-CBZ-Phe-Arg-AMC TFA (Z-FR-AMC TFA) is a fluorescent substrate for serine proteases. assess the activity of trypsin, plasmin, and cathepsin.</p>Formel:C35H37F3N6O8Reinheit:99.88%Farbe und Form:SolidMolekulargewicht:726.7VK13
<p>VK13 (Compound 6) is a potent inhibitor of human cathepsin L (hCatL) and SARS-CoV-2 3CLpro (3CL-PR), with Ki values of 2.6 nM and 0.55 nM, respectively. It also exhibits activity against CoV-2, with an EC50 value of 1.25 μM.</p>Formel:C24H28N4O5Farbe und Form:SolidMolekulargewicht:452.5036,6′-Dihydroxythiobinupharidine
CAS:<p>6,6′-Dihydroxythiobinupharidine, a cysteine proteases inhibitor, amplifies DNA cleavage facilitated by human topoisomerase IIα and IIβ by approximately 8-fold</p>Formel:C30H42N2O4SFarbe und Form:SolidMolekulargewicht:526.73Z-L(D-Val)G-CHN2
<p>Z-L(D-Val)G-CHN2, an isoform of Z-LVG-CHN2, serves as a cell-permeable and irreversible inhibitor of cysteine proteinase.</p>Formel:C22H31N5O5Reinheit:98%Farbe und Form:SolidMolekulargewicht:445.51Z-Phe-Tyr(tBu)-diazomethylketone
CAS:<p>Irreversible cathepsin L inhibitor which is ca 10'000 times more effective in inactivating cathepsin L than cathepsin S.</p>Formel:C31H34N4O5Farbe und Form:SolidMolekulargewicht:542.636Cathepsin K inhibitor 7
<p>Cathepsin K Inhibitor7 (compound 7) is an inhibitor of Cathepsin K, exhibiting a pKi value of 7.3. It is utilized in research on osteoporosis.</p>Farbe und Form:Odour Solid
