Protease-aktivierte Rezeptoren

Protease-aktivierte Rezeptor (PAR)-Inhibitoren sind Verbindungen, die die Aktivität von PARs hemmen, einer Familie von G-Protein-gekoppelten Rezeptoren, die durch proteolytische Spaltung aktiviert werden. Diese Rezeptoren spielen eine Rolle in verschiedenen physiologischen Prozessen, einschließlich Gerinnung, Entzündung und Gewebereparatur. PAR-Inhibitoren sind wertvolle Werkzeuge zur Untersuchung der Mechanismen dieser Prozesse und ihrer Beteiligung an Krankheiten wie Krebs, Herz-Kreislauf-Erkrankungen und chronischen Entzündungen. Bei CymitQuimica bieten wir PAR-Inhibitoren an, um Ihre Forschung in den Bereichen Signaltransduktion, Immunantwort und therapeutische Entdeckung zu unterstützen.

53 Produkte aus dem Bereich "Protease-aktivierte Rezeptoren" gefunden

Reinheit (%)

100

Produkte pro Seite.

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TRAP-6 amide TFA
CAS:
- 1426807-16-0
TRAP-6 amide TFA is a PAR-1 thrombin receptor agonist peptide.
Formel:C₃₆H₅₈F₃N₁₁O₁₀
Farbe und Form:Solid
Molekulargewicht:861.922
Ref: TM-T38887
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P4pal10 TFA
P4pal10 TFA, the TFA salt form of P4pal10, serves as an antagonist of the protease-activated receptor 4 (PAR4). This compound inhibits platelet aggregation and thrombin generation induced by tissue factor (TF), exhibiting anticoagulant and antithrombotic activities. Additionally, P4pal10 TFA alleviates carrageenan-induced edema and neutrophil infiltration, and ameliorates damage in rat myocardial ischemia/reperfusion (I/R) models.
Farbe und Form:Odour Solid
Ref: TM-TP2784
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TRAP-5 amide
CAS:
- 141923-41-3
TRAP-5 amide is a peptide agonist for protease-activated receptor 1 (PAR 1) [1].
Formel:C₃₀H₅₁N₉O₆
Farbe und Form:Solid
Molekulargewicht:633.78
Ref: TM-T80111
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PAR 4 (1-6) (TFA)
PAR 4 (1-6) TFA (GYPGQV TFA), a hexapeptide derived from protease-activated receptor 4 (PAR 4), serves as a specific agonist for PAR 4.
Formel:C₂₈H₄₁N₇O₉·xC₂HF₃O₂
Farbe und Form:Solid
Ref: TM-T75904
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FLLRN
CAS:
- 141136-84-7
FLLRN is a biologically active peptide serving as a PAR1-specific antagonist.
Formel:C₃₁H₅₁N₉O₇
Farbe und Form:Solid
Molekulargewicht:661.79
Ref: TM-T78545
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Parstatin(mouse)
CAS:
- 1065756-01-5
Peptide inhibits endothelial migration/proliferation (IC50 ~20μM), induces cell cycle arrest, triggers apoptosis, and has cardioprotective effects.
Formel:C₁₈₉H₃₂₆N₅₈O₅₇S₃
Reinheit:98%
Farbe und Form:Solid
Molekulargewicht:4419.19
Ref: TM-TP1966
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YFLLRNP
CAS:
- 149440-16-4
YFLLRNP is a biologically active peptide functioning as a partial agonist of PAR-1, selectively activating the G12/13 signaling pathway.
Formel:C₄₅H₆₇N₁₁O₁₀
Farbe und Form:Solid
Molekulargewicht:922.08
Ref: TM-T80235
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Parstatin(human)
CAS:
- 1065755-99-8
Cell-permeable PAR1-derived peptide; inhibits endothelial migration, proliferation (IC50 ~3μM), induces apoptosis, and has cardioprotective effects.
Formel:C₁₉₁H₃₃₀N₆₄O₅₃S₃
Reinheit:98%
Farbe und Form:Solid
Molekulargewicht:4467.29
Ref: TM-TP1965
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2-Furoyl-LIGRLO-amide
CAS:
- 729589-58-6
2-Furoyl-LIGRLO-amide TFA is a peptide that acts as a proteinase-activated receptor-2 (PAR2) agonist, and contains a furoyl group addition at its N-terminal.
Formel:C₃₆H₆₃N₁₁O₈
Reinheit:98%
Farbe und Form:Solid
Molekulargewicht:777.95
Ref: TM-TP1478
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PAR650097
PAR650097 is a humanized monoclonal antibody targeting PAR2, used in migraine research.
Reinheit:96.67% (SEC-HPLC) - 98.83% (SEC-HPLC)
Farbe und Form:Liquid
Molekulargewicht:145.5kDa
Ref: TM-T77402
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tcY-NH2
CAS:
- 327177-34-4
Selective PAR4 antagonist peptide. Inhibits endostatin release and platelet aggregation induced by thrombin.
Formel:C₄₀H₄₉N₇O₇
Reinheit:98%
Farbe und Form:Solid
Molekulargewicht:739.87
Ref: TM-TP1925
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PZ-128
CAS:
- 371131-16-7
PZ-128, a PAR1 antagonist, is used potentially for the treatment of thrombosis.
Formel:C₅₅H₉₉N₁₃O₉
Reinheit:98%
Farbe und Form:Solid
Molekulargewicht:1086.46
Ref: TM-T28477
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FSLLRY-NH2
CAS:
- 245329-02-6
PAR2 antagonist; counters taxol effects, PKC in mice; inhibits ERK, collagen in fibroblasts; lessens dermatophyte itch in mice.
Formel:C₃₉H₆₀N₁₀O₈
Reinheit:98%
Farbe und Form:Solid
Molekulargewicht:796.97
Ref: TM-TP1904
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Protease-Activated Receptor-1, PAR-1 Agonist TFA
PAR-1 Agonist TFA: Selective peptide, mimics thrombin, activates PAR-1 receptor.
Farbe und Form:Liquid
Ref: TM-T36288
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AY 254
CAS:
- 2093408-03-6
AY 254: Potent PAR2 agonist, ERK1/2 activation (EC50=2 nM), limits caspase 3/8, aids HT29 cell healing, boosts IL-8.
Formel:C₃₀H₄₉N₉O₆
Farbe und Form:Solid
Molekulargewicht:631.779
Ref: TM-T41189
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Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2
CAS:
- 211190-38-4
Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2 is a biologically active peptide functioning as a selective agonist for Protease Activated Receptor 1 (PAR-1), a subtype
Formel:C₄₂H₆₃FN₁₂O₈
Farbe und Form:Solid
Molekulargewicht:883.02
Ref: TM-T80240
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PAR-2 (1-6) (human)
CAS:
- 202933-49-1
PAR-2 (1-6) (human) (SLIGKV), a peptide ligand, is a PAR-2 agonist [1] .
Formel:C₂₈H₅₃N₇O₈
Farbe und Form:Solid
Molekulargewicht:615.76
Ref: TM-T76650
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SFNGGP-NH2
CAS:
- 261521-21-5
SFNGGP-NH2 is a biologically active peptide that interacts with Protease-Activated Receptor 3 (PAR-3), a high-affinity thrombin receptor.
Formel:C₂₅H₃₆N₈O₈
Farbe und Form:Solid
Molekulargewicht:576.6
Ref: TM-T80234
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Protease-Activated Receptor-1, PAR-1 Agonist
CAS:
- 141136-85-8
Selective peptide agonist that mimics thrombin to activate PAR-1 receptor, enabling targeted receptor activation.
Formel:C₃₅H₅₈N₁₀O₉
Farbe und Form:Solid
Molekulargewicht:762.91
Ref: TM-T38836
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Parstatin(human) TFA
Parstatin(human) TFA, a cell-penetrating PAR-1 thrombin receptor agonist peptide, effectively inhibits angiogenesis, as indicated by studies [1] [2].
Formel:C₁₉₃H₃₃₁F₃N₆₄O₅₅S₃
Farbe und Form:Solid
Molekulargewicht:4581.28
Ref: TM-T75873