ALK
ALK-Inhibitoren sind Verbindungen, die gezielt die anaplastische Lymphomkinase (ALK), eine Rezeptor-Tyrosinkinase, hemmen, die an der Entwicklung und dem Fortschreiten bestimmter Krebsarten, einschließlich nicht-kleinzelligem Lungenkrebs und Neuroblastom, beteiligt ist. Durch die Hemmung von ALK blockieren diese Verbindungen Signalkaskaden, die das Wachstum und Überleben von Tumorzellen fördern. Bei CymitQuimica bieten wir ALK-Inhibitoren an, um Ihre Forschung in der Onkologie, bei zielgerichteten Krebstherapien und in der Signaltransduktion zu unterstützen.
136 Produkte aus dem Bereich "ALK" gefunden
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ALK inhibitor 1
CAS:ALK inhibitor 1 is a selective ALK kinase inhibitor.Formel:C23H28BrN7O3SReinheit:98.27%Farbe und Form:SolidMolekulargewicht:562.48Ref: TM-T10285
1mg50,00€5mg110,00€10mg166,00€25mg323,00€50mg447,00€100mg610,00€1mL*10mM (DMSO)136,00€ALK-IN-26
CAS:ALK-IN-26 is an ALK inhibitor with potential anticancer activity.ALK-IN-26 shows antiproliferative activity against glioblastoma.Formel:C24H23NO3SReinheit:99.91%Farbe und Form:SoildMolekulargewicht:405.51ZX-29
CAS:ZX-29: Strong ALK inhibitor; IC50 - ALK 2.1 nM, L1196M 1.3 nM, G1202R 3.9 nM; triggers autophagy; anti-cancer.Formel:C23H28ClN7O3SReinheit:98.32%Farbe und Form:SolidMolekulargewicht:518.03Ref: TM-T13416
1mg92,00€5mg230,00€10mg364,00€25mg620,00€50mg848,00€100mg1.121,00€200mg1.510,00€1mL*10mM (DMSO)264,00€F-1
CAS:F-1: Potent ALK/ROS1 inhibitor with 2.1-3.9 nM IC50s; suppresses p-ALK signaling.Formel:C22H27ClN8O3SReinheit:97.66%Farbe und Form:SolidMolekulargewicht:519.02Ref: TM-T11254
1mg70,00€5mg133,00€10mg178,00€25mg299,00€50mg424,00€100mg587,00€200mg800,00€1mL*10mM (DMSO)165,00€Ascrinvacumab
CAS:Ascrinvacumab (PF-03446962): humanized IgG2 anti-ALK-1 antibody, Kd 7 nM, inhibits TGF-β, for HCC research.Reinheit:SDS-PAGE:95% SEC-HPLC:98.18%Farbe und Form:LiquidMolekulargewicht:150 kDaMS4078
CAS:MS4078 is an inhibitor and aplastic lymphoma kinase (ALK) PROTAC (degrader) based on Cereblon ligand, with a Kd of 19 nM for binding affinity to ALK.Formel:C45H52ClN9O8SReinheit:98.74%Farbe und Form:SolidMolekulargewicht:914.47Ref: TM-T16153
1mg49,00€2mg66,00€5mg90,00€10mg152,00€25mg260,00€50mg416,00€100mg615,00€1mL*10mM (DMSO)152,00€ALK inhibitor 2
CAS:ALK inhibitor 2 is a new-type and selective inhibitor for the ALK kinase.Formel:C23H28ClN7O3SReinheit:99.77% - >99.99%Farbe und Form:SolidMolekulargewicht:518.03CEP-28122 mesylate salt (1022958-60-6 free base)
CEP-28122 mesylate salt (1022958-60-6 free base) is a highly selective orally active ALK inhibitor (IC50: 1.9 nM in an enzyme-based TRF assay).Formel:C29H39ClN6O6SReinheit:99.79%Farbe und Form:SolidMolekulargewicht:635.17M4K2234
CAS:M4K2234 (26b) inhibits ALK2/ALK5 (IC50: 5/2144 nM), used as a probe for ALK1/2 kinases in cancer research.Formel:C27H31FN4O2Reinheit:99.99%Farbe und Form:SolidMolekulargewicht:462.56TL13-12
CAS:TL13-12 is a selective degrader of ALK-PROTAC and inhibits ALK activity (IC50: 0.69 nM).Formel:C45H53ClN10O10SReinheit:98%Farbe und Form:SolidMolekulargewicht:961.49dALK-3
dALK-3 is a degrader of anaplastic lymphoma kinase (ALK) that effectively induces the degradation of EML4-ALK with a DC50 of 0.182 μM. It exhibits significant antiproliferative activity against H3122 cells and is applicable for tumor research.Formel:C39H45ClN7O5PFarbe und Form:SolidMolekulargewicht:758.245ALK-IN-13
CAS:ALK-IN-13 is an ALK inhibitor.
Formel:C29H39ClN7O2PFarbe und Form:SolidMolekulargewicht:584.1FDA-Approved Kinase Inhibitor Library
A unique collection of 263 kinase inhibitors/regulators for specific targeting of kinases, ready for high-throughput screening and high-content screening.
Farbe und Form:LiquidKinase Inhibitor Library
A unique collection of 2720 kinase inhibitors/regulators for high throughput screening and high content screening for drug discovery in kinase related diseases;Farbe und Form:Odour SolidRef: TM-L1600
1mgNachfragen30μL*10mM (DMSO)Nachfragen50μL*10mM (DMSO)Nachfragen100μL*10mM (DMSO)Nachfragen250μL*10mM (DMSO)NachfragenLDN 193688
CAS:LDN 193688 is a BMP kinase inhibitor preferential for the ALK2 site, acting by binding to the ALK site,progressive osseous fibrodysplasia.Formel:C22H16N4OReinheit:99.48%Farbe und Form:SoildMolekulargewicht:352.39Multi-kinase-IN-6
Multi-kinase-IN-6 (compound 10e) is a multikinase inhibitor that effectively impedes the activity of TrkA, ALK2, c-KIT, EGFR, PIM1, CK2α, CHK1, and CDK2.Reinheit:98%Farbe und Form:Odour SolidCPD-1224
CAS:CPD-1224, an oral ALK inhibitor derivative, binds cereblon, targets EML4-ALK fusions, and degrades ALK plus L1196M/G1202R mutants.Formel:C43H47ClN8O7SFarbe und Form:SolidMolekulargewicht:855.4TL13-112
CAS:TL13-112 is a selective degrader of ALK-PROTAC and inhibits ALK activity (IC50: 0.14 nM).Formel:C49H60ClN9O10SReinheit:98%Farbe und Form:SolidMolekulargewicht:1002.57ALK-IN-9
CAS:ALK-IN-9 effectively inhibits cell growth with IC50 <0.2 nM for Ba/F3-EML4-ALK, KM12, KG-1.Formel:C20H21FN6O3Farbe und Form:SolidMolekulargewicht:412.425ALK-IN-12
CAS:ALK-IN-12: potent ALK inhibitor (IC50: 0.18 nM), affects IGF1R and InsR (IC50: 20.3/90.6 nM), potential for cancer therapy.Formel:C24H30ClN6O2PFarbe und Form:SolidMolekulargewicht:500.97
