Sigma-Rezeptor

Roluperidone (CYR-101) is a novel cyclic amide derivative. It has high equipotent affinities for 5-HT2A …

Amitriptyline hydrochloride (Annoyltin) is the hydrochloride salt of the tricyclic dibenzocycloheptadiene amitriptyline with antidepressant and …

Glycerol phenylbutyrate (HPN-100) (GPB) is a new generation ammonia scavenger drug and it also is …

Blonanserin (AD-5423) is an atypical antipsychotic approved in Japan in January, 2008. Relative to many …

4-PPBP maleate is a potent σ1 receptor (ligand) agonist. 4-PPBP maleate can be considered a …

KB-5492 FA is a selective sigma receptor inhibitor with antiulcerogenic effects.CAS 번호128-52-56-8

Compound 8b hydrochloride, a selective S1R agonist, exhibits affinity with K i s of 1.1 …

S1R Agonist 1 (Compound 6b) hydrochloride is a selective S1R agonist, displaying K i values …

Sigma-1 receptor antagonist 5 (compound 12), a 4-pyridylpiperidine derivative, exhibits analgesic properties through its antagonistic …

KSK67 is a selective dual antagonist of sigma-2 and histamine H3 receptors with inhibitory effects …

Glycerol phenylbutyrate-D5 is a deuterium-labeled Glycerol phenylbutyrate. Glycerol phenylbutyrate is a sigma-2 (σ2) receptor ligand …

S1RA (E-52862)(E-52862) is a potent, selective antagonist of the sigma-1 receptor (σ1R, Ki=17 nM), demonstrating …

S1R agonist 2 is a selective S1R agonist with a Ki of 88 nM for …

AD186, a potent and selective S1R agonist, exhibits dissociation constants (Kis) of 2.7 nM for …

AB21 oxalate, a potent and selective S1R antagonist, exhibits binding affinities (Kis) of 13 nM …

WLB-89462 (Compound 20c) is a selective σ2 receptor ligand with a K i of 13 …

Sigma-LIGAND-1 is a selective Sigma Receptor ligand with an IC50s of 16 nM, 19 nM …

PD 144418 oxalate is a highly potent and selective sigma 1 (σ1) receptor ligand, displaying …

NE-100 hydrochloride (NE-100 HCl) is a potent and selective antagonist of σ1 (IC50 = 4.16 …

Sigma-1 receptor antagonist 4 (Compound 32) is a potent σ1R antagonist that significantly enhances morphine's …

Glycerol phenylbutyrate-D15 is a deuterium-labeled Glycerol phenylbutyrate. Glycerol phenylbutyrate is a sigma-2 (σ2) receptor ligand …

BMY-14802 hydrochloride (BMS 181100 hydrochloride) is a selective antagonist of σ receptor (IC50 = 112 …

KB-5492 free base is an orally available, selective antiulcer agent that inhibits sigma receptors and …

BMY-14802 (alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol) is a selective and orally active sigma-1 antagonist with an IC50 of …

AB21 HCl is a selective antagonist of the σ1 receptor, with Kis of 13 nM …

BD1063 dhydrochloride is a potent and selective sigma 1(σ1) receptor antagonist(Ki = 9 nM).

4-IBP is a selective σ1 agonist with a high level of affinity for the σ1 …

L-745870 trihydrochloride is a highly potent and selective D4 dopamine receptor antagonist.

Amitriptyline (MK-230, N-750, Ro41575) is a tricyclic antidepressant (TCA) with analgesic properties. Amitriptyline is widely …

Sigma-1 receptor antagonist 2 is a more potent and selective antagonist of sigma 1 receptor …

σ1 Receptor antagonist-1 is a selective sigma 1 receptor antagonist.

Cutamesine dihydrochloride (SA4503 dihydrochloride) is a selective σ1 receptor agonist (IC50: 17.4 nM). It shows …

Sigma-1 receptor antagonist 3 is a more potent and selective antagonist of Sigma-1 (σ1) receptor …

EST64454 hydrochloride (EST64454) is a highly soluble σ1 receptor antagonist (Ki : 22 nM),has the …

Siramesine hydrochloride (Lu 28-179 hydrochloride) is a selective sigma-2 receptor agonist, which has been shown …

PRE-084 hydrochloride is a selective agonist of σ1(IC50:44 nM, in the sigma receptor assay).

BD 1008 dihydrobromide is a selective antagonist of the sigma 1 (σ1) receptor (Ki = …

Dimemorfan phosphate (3,17-dimethylmorphinan) is a sigma 1 receptor agonist. Dimemorfan phosphate is used as a …

Blarcamesine hydrochloride (AVex-73 hydrochloride) is a Sigma-1 Receptor agonist (IC50: 860 nM).

S1RA hydrochloride (E-52862 hydrochloride) is an effective and specific sigma-1 receptor(σ1R, Ki: 17 nM) antagonist, …

Blarcamesine (AVex-73) is a muscarinic M1 agonist potentially for the treatment of Alzheimer's disease.

Sigma-1 receptor antagonist 1 is an effective and selective antagonist of sigma-1 receptor. Sigma-1 receptor …

Ditolylguanidine (Di-o-tolylguanidine) is an agonist of sigma receptor (σ1/σ2 receptor).

BD-1047 dihydrobromide (BD1047.2HBr) , a selective functional antagonist of sigma receptors, has antipsychotic activity in …

Siramesine (Lu 28-179)(Lu 28-179) is a selective sigma-2 receptor agonist, which has been shown to …

Pre-084 is a high affinity, selective σ1 agonist.

PD 144418 displays potential antipsychotic activity. PD 144418 is a high affinity, potent and selective …

SARS-CoV-2-IN-57 (compound (+)-R-26) is a potent inhibitor of SARS-CoV-2 with an IC50 of 80 nM …