API-Verunreinigungen

Lomustine Related Compound D (3-(2-Chloroethyl)-1-cyclohexyl-1-nitrosourea)

Benzophenone (Diphenylmethanone)

Latanoprost Related Compound A (Isopropyl (E)-7-{(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl}-5-heptenoate)

Cilostazol Related Compound A (6-hydroxy-3,4-dihydro-1H-quinolin-2-one)

Desloratadine Related Compound F (8-Chloro-6,11-dihydro-11-(N-formyl-4-piperidinylidene) -5H-benzo[5,6]cyclohepta[1,2-b]pyridine)

Valsartan Related Compound B (N-butyryl-N-{[2'-(1H-tetrazole-5-yl)-biphenyl-4-yl]methyl}-L-valine)

Haloperidol Related Compound A (4,4'-Bis[4-(p-chlorophenyl)-4-hydroxypiperidino]-butyrophenone)

Bisoprolol Related Compound D (1-(4-{[(2-Isopropoxyethoxy)methoxy]methyl}phenoxy)-3-(isopropylamino)propan-2-ol fumarate (2:1) salt)

Lamotrigine Related Compound C (3-amino-6-(2,3-dichlorophenyl)-1,2,4-triazin-5(4H)-one)

Cyclophosphamide Related Compound B (3-(2-chloroethyl)-2-oxo-2-hydroxy-1,3,6,2-oxadiazaphosphonane)

Atenolol Related Compound E (2,2'-{[(2-Hydroxypropane-1,3-diyl)bis(oxy)]bis(4,1-phenylene)}diacetamide)

Metoclopramide Related Compound B (Methyl 4-acetamido-5-chloro-2-methoxybenzoate)

Timolol Related Compound F (3-Chloro-4-morpholino-1,2,5-thiadiazol)

Sumatriptan Succinate Related Compound C ([3-[2-(dimethylamino)ethyl]-1-(hydroxymethyl)-1H-indol-5-yl]-N-methylmethanesulfonamide succinate salt)

Cefuroxime Axetil δ-3-Isomers ((1RS,6R,7R)-1-Acetoxyethyl 3-[(carbamoyloxy)methyl]-7-[(Z)-2-(furan-2-yl)-2-(methoxyimino)acetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-3-ene-2-carboxylate)

Pyrantel Related Compound A ((Z)-1-Methyl-2-[2-(2-thiophenyl)vinyl]-1,4,5,6-Tetrahydropyrimidine 4,4'-methylenebis[3-hydroxy-2-naphthoate] (1:1))

Proguanil Related Compound C (1,5-bis(4-chlorophenyl)biguanide hydrochloride)

Desloratadine Related Compound B (8-chloro-11-(1,2,3,6-tetrahydropyridin-4-yl)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine hydrochloride)

(Z)-N'-Methylmeloxicam ((Z)-N-(3,5-dimethylthiazol-2(3H)-ylidene)-4-hydroxy-2-methyl-2H-benzo[e][1,2]thiazine-3-carboxamide 1,1-dioxide)

Ethosuximide Related Compound A (2-Ethyl-2-methylsuccinic acid)

Norfloxacin Related Compound H (7-[4-(ethoxycarbonyl)piperazin-1-yl]-1-ethyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid)

Cetirizine Related Compound C (2-(2-{4-[(4-Chlorophenyl)phenylmethyl]piperazin-1-yl}ethoxy)acetamide)

Citalopram Related Compound H (1-(4'-fluorophenyl)-1-(3-dimethylaminopropyl)-5-bromophthalane hydrobromide)

Metaxalone Related Compound B (1-amino-3-(3,5-dimethylphenoxy)propan-2-ol)

Atenolol Related Compound B (2-[4-(2,3-Dihydroxypropoxy)phenyl]acetamide)

Olanzapine Related Compound B (2-methyl-10H-thieno-[2,3-b][1,5]benzodiazepin-4[5H]-one)

Glimepiride Related Compound B (glimepiride sulfonamide, or 3-Ethyl-4-methyl-2-oxo-N-(4-sulfamoylphenethyl)-2,5-dihydro-1H-pyrrole-1-carboxamide)

Desogestrel Related Compound B (13-Ethyl-3-hydroxy-11-methylene-18,19-dinor-17α-pregn-4-en-20-yn-17-ol)

Spironolactone Related Compound B ((2'R)-7α-(Acetylthio)-5'H-spiro[androst-4-ene-17,2'-furan]-3,5'-dione)

Rivastigmine Related Compound B ((R,S)-3-[1-(Dimethylamino)ethyl]phenyl dimethylcarbamate)

Ecamsule Related Compound F (4-((E)-((1SR,4SR)-7,7-dimethyl-3-oxo-4-(sulfomethyl)bicyclo[2.2.1]heptan-2-ylidene)methyl)benzoic acid)

Ketoprofen Related Compound F (3-(1-Cyanoethyl)benzophenone)

Molindone Related Compound A (3-Ethyl-2-methyl-1,5,6,7-tetrahydro-4H-indol-4-one)

Aripiprazole Related Compound B (7-(4-hydroxy-butoxy)-3,4-dihydroquinolin-2(1H)-one)

Pramipexole Related Compound D ((R)-2-Amino-4,5,6,7-tetrahydro-6-(propylamino)benzothiazole dihydrochloride)

Clomipramine Related Compound D (3-(3,7-Dichloro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethylpropan-1-amine hydrochloride)

Clarithromycin Impurity D (N-desmethyl clarithromycin)

Chlorpheniramine Related Compound B (di(pyridin-2-yl)amine)

Pyrazinamide Related Compound A (Pyrazinecarboxylic acid)

Dicyclomine Related Compound A ([1,1'-Bi(cyclohexane)]-1-carboxylic acid)

Drometrizole Trisiloxane Related Compound E (2-(2H-Benzotriazol-2-yl)-6-{3-[bis(trimethylsiloxy)methylsilyl]isobutyl}-O1-[bis(trimethylsiloxy)methylsilyl]-p-cresol)

3-O-Methylmethyldopa

Sulindac Related Compound B ((Z)-2-{5-fluoro-2-methyl-1-[4-(methylsulfonyl)benzylidene]-1H-inden-3-yl}acetic acid)

Oxybutynin Related Compound A (Phenylcyclohexylglycolic Acid)

Zolmitriptan Related Compound F (2,2'-[4-(Dimethylamino)butane-1,1-diyl]bis{5-[(S)-(2-oxooxazolidin-4-yl)methyl]-3-(2-dimethylaminoethyl)indole})

Lisinopril Related Compound A ((S)-2-{(3S,8aS)-3-(4-aminobutyl)-1,4-dioxohexahydropyrrolo[1,2-α]pyrazin-2(1H)-yl}-4-phenylbutanoic acid)

Perindopril Related Compound E ((2S,3aS,7aS)-1-{(S)-2-[(S)-1-Isopropoxy-1-oxopentan-2-ylamino]propanoyl}octahydro-1H-indole-2-carboxylic acid, tert-butylamine)

Cyproheptadine Related Compound C (5-(1-methyl-piperidin-4-yl)-5H-dibenzo[a,d]cyclohepten-5-ol)

Ramipril Related Compound D (Ethyl (S)-2-[(3S,5aS,8aS,9aS)-3-methyl-1,4-dioxodecahydro-2H-cyclopenta[4,5]pyrrolo[1,2-a]pyrazin-2-yl]-4-phenylbutanoate)

Rivastigmine Related Compound A ((+)-Di-(p-toluoyl)-D-tartaric acid)

Doxepin Related Compound A (dibenzo[b,e]oxepin-11(6H)-one)

Drometrizole Trisiloxane Related Compound C (2-(2H-Benzotriazol-2-yl)-6-(isobuten-1-yl)-O1-[bis(trimethylsiloxy)methylsilyl]-p-cresol)

Levofloxacin Related Compound F ((S)-2,3-Dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de][1,4]benzoxazine-6-carboxylic acid)

Perphenazine Sulfoxide

Felbamate Related Compound B (Phenethyl carbamate)

Propafenone Related Compound A (N-{2-Hydroxy-3-[2-(3-phenylpropanoyl)phenoxy]propyl}-N-propylformamide)

Nebivolol Related Compound C ((RS)-6-Fluoro-2-[(RS)-oxiran-2-yl]chroman)

Iopamidol Related Compound A (N,N'-Bis-(1,3-dihydroxy-2-propyl)-5-amino-2,4,6-triiodoisophthalamide)

Flunixin Related Compound B (2-Methyl-3-(trifluoromethyl)aniline)

Clonidine Related Compound B (2-[(E)-2,6-dichlorophenylimino]-1-(1-{2-[(E)-2,6-dichlorophenylimino]-imidazolidin-1-yl}-ethyl)-imidazolidine)

(E)-Thiothixene

Phenytoin Related Compound B (2,2-Diphenyl-2-ureidoacetic acid)

Sulindac Related Compound C ((Z)-2-{5-fluoro-2-methyl-1-[4-(methylthio)benzylidene]-1H-inden-3-yl}acetic acid)

Milnacipran Related Compound B (1-Phenyl-3-azabicyclo[3.1.0]hexan-2-one)

Clobetasol Propionate Related Compound A (9α-Fluoro-11β-hydroxy-16β-methyl 3-oxo-androsta-1,4-diene-17(R)-spiro-2'-[4'-chloro-5'-ethylfuran-3'(2'H)-one])

Doxazosin Related Compound E (2,4-dichloro-6,7-dimethoxyquinazoline)

Verapamil Related Compound F ((3,4-Dimethoxyphenyl)methanol)

Buspirone Related Compound L (8-(4-Chlorobutyl)-8-azaspiro[4.5]decane-7,9-dione)

Moexipril Related Compound C ((S)-tert-butyl 2-{(S)-2-[(S)-1-ethoxy-1-oxo-4-phenylbutan-2-ylamino]propanoyl}-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylate, maleate)

Loperamide Related Compound F (1r,4s)-4-(4-Chlorophenyl)-1-[4-(dimethylamino)-4-oxo-3,3-diphenylbutyl]-4-hydroxypiperidine 1-oxide hydrate)

Clarithromycin Impurity H (3""-N-Demethyl-3""-N-formyl-6-O-methylerythromycin A)

Mefloquine Related Compound A (threo-mefloquine)

Citalopram Related Compound E (1-(3-dimethylaminopropyl)-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile-N-oxide hydrochloride)

Sevoflurane Related Compound C (0.2 mL) (1,1,1,3,3,3-hexafluoro-2-propanol)

Methoxsalen Related Compound B (4,9-Dimethoxy-7H-furo[3,2-g]chromen-7-one)

Cevimeline trans-Isomer ((2RS,2'SR)-2'-Methyl-4-azaspiro{bicyclo[2.2.2]octane-2,5'-[1,3]oxathiolane} hydrochloride hemihydrate)

Indomethacin Related Compound B (4-chlorobenzoic acid)

Tacrolimus 8-propyl analog (See USP Certificate for full Chemical Name)

Acamprosate Related Compound A (3-aminopropane-1-sulfonic acid)

Diclofenac Related Compound A (N-(2,6-dichlorophenyl)indolin-2-one)

Etonogestrel Related Compound C (13-Ethyl-17β-hydroxy-11-methylene-18,19-dinor-17α-pregn-4-en-20-yn-3,6-dione)

5-Phenylhydantoin

Flutamide Related Compound B (N-[4-nitro-3-(trifluoromethyl)phenyl]acetamide)

Orphenadrine Related Compound A ((RS)-N,N-dimethyl-2-[(3-methylphenyl)-phenylmethoxy]ethanamine citrate) (AS)

Bosentan Related Compound B (4-(tert-butyl)-N-[6-hydroxy-5-(2-methoxyphenoxy)-(2,2'-bipyrimidin)-4-yl]benzenesulfonamide)

Benztropine Related Compound A ((1R,3r,5S)-3-(Benzhydryloxy)-8-azabicyclo[3.2.1]octane hydrochloride)

Glyburide Related Compound B (methyl-[[4-[2-[(5-chloro-2-methoxybenzoyl)-amino]ethyl]phenyl]sulfonyl]carbamate) (AS)

Mycophenolate Mofetil Related Compound B [(RS)-7-hydroxy-5-methoxy-4-methyl-6-[2-(5-methyl-2-oxo-tetrahydrofuran-5-yl)ethyl]-3H-isobenzofuranyl-1-one]

Bendamustine Related Compound C (Ethyl 4-{5-[bis(2-hydroxyethyl)amino]-1-methyl-1H -benzimidazol-2-yl}butanoate)

Amoxicillin Related Compound I ((R)-2-Amino-2-(4-hydroxyphenyl)acetic acid)

Fluoxetine Related Compound C (4-(methyl{3-phenyl-3-[4-(trifluoromethyl)phenoxy]propyl}amino)-4-oxobutanoic acid)

Tiotropium Related Compound C ((1R,3s,5S)-3-[2-Hydroxy-2,2-di(thiophen-2-yl)acetoxy]-8,8-dimethyl-8-azabicyclo[3.2.1]oct-6-en-8-ium bromide)

Atomoxetine Related Compound C (N-methyl-3-phenyl-3-(p-tolyloxy)propan-1-amine hydrochloride)

Tolcapone Related Compound B (4-hydroxy-3-methoxy-4'-methyl-5-nitrobenzophenone)

Oxazepam Related Compound A (7-Chloro-5-phenyl-4,5-dihydro-1H-benzodiazepine-2,3-dione)

Piroctone Related Compound A ((2-[5-methyl-3-(2,4,4-trimethylpentyl)-4,5-dihydroisoxazol-5-yl]acetic acid) 2-aminoethanol salt)

Amlodipine Related Compound F (Dimethyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate maleate)

Ramipril Related Compound A ((2S,3aS,6aS)-1-[(S)2-[[(S)-1-(Methoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-octahydrocyclopenta[b]pyrrole-2-carboxylic acid)

Desfluoro Aprepitant (5-{[(2R,3S)-2-{(R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy}-3-phenylmorpholino]methyl}-2H-1,2,4-triazol-3(4H)-one)

Methylene Simvastatin ((1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl 2,2-dimethylbut-3-enoate)