H-Phe-Arg-βNA · 2 HCl

CAS: 100929-99-5

Ref. 01-4000885

Produktinformation

• Name: H-Phe-Arg-βNA · 2 HCl
• Synonyme: MC-207110, H-Phe-Arg-.beta.NA . 2 HCl, Phe-Arg Beta-Naphthylamide Dihydrochloride

Beschreibung

Substrate for dipeptidyl aminopeptidase I (cathepsin C). A broad-spectrum efflux pump inhibitor in gram-negative bacteria. PAbN has been evaluated as an adjunct to antibiotics, as efflux in bacteria mediates antibiotic resistance. Vecchione et al. demonstrated that Phe-Arg-β-naphthylamide could potentiate drug activity also against a gram-positive bacterium. PAbN permeabilizes the outer membrane of gram-negative bacteria (Lamers et al.).

• Marke: Bachem

Chemische Eigenschaften

• Molekulargewicht: 519.47
• Formel: C₂₅H₃₀N₆O₂HCl
• Reinheit: > 99%
• Farbe/Form: White Powder