SASRIN™ resin (200-400 mesh, 0.80-1.20 mmol/g)

CAS: 124760-64-1

Ref. 01-4012712

Produktinformation

• Name: SASRIN™ resin (200-400 mesh, 0.80-1.20 mmol/g)
• Synonyme: 3-CH₃O-4-HOCH₂-Ph-O-CH₂-Ph-polymer, 2-Methoxy-4-alkoxybenzyl alcohol resin (200-400 mesh)

Beschreibung

SASRIN™ (=Super Acid Sensitive ResIN) was developed in our own laboratories especially for Fmoc solid phase synthesis (EP 0 292 729, US 4,831,084 and US 4,914,151). Its high acid lability enables the cleavage and isolation of the protected peptide fragment. Beside SPPS SASRIN™ has been used in several organic reactions like the synthesis of 4-aryl substituted β-lactams employing Suzuki and Heck couplings, the synthesis of β-sultams, quinazoline-2,4-diones, pyridines and pyrido[2,3-d]pyrimidines and the generation of secondary alkylamines by borane reduction. S.S.Rahman et al. reported on the FT-IR and Raman spectroscopic monitoring of reactions on a single SASRIN™ bead and C.L.Brummel et al. on the evaluation of mass spectrometric methods applicable to the direct analysis of non-peptide bead-bound combinatorial libraries. For a review on the manifold applications of our SASRIN™ resin, including many useful procedures, please ask for our SASRIN™ brochure.

• Marke: Bachem

Chemische Eigenschaften

• Molekulargewicht: n/a
• Formel: na
• Farbe/Form: Light Brown Powder