Ac-muramyl-Ala-D-Glu(Lys(stearoyl)-OH)-NH₂

CAS: 78113-36-7

Ref. 01-4015937

Produktinformation

• Name: Ac-muramyl-Ala-D-Glu(Lys(stearoyl)-OH)-NH₂
• Synonyme: MDP-Lys(L 18), (2R)-2-{[(4R)-4-{[(2S)-2-{[(2R)-2-{[(3R,4R,5S,6R)-3-(acetylamino)-2,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yl]oxy}propanoyl]amino}propanoyl]amino}-5-amino-5-oxopentanoyl]amino}-6-(octadecanoylamino)hexanoic acid (non-preferred name), 1: PN: WO2009033811 PAGE: 103 claimed protein, <span class="text-smallcaps">L</smallcap>-Lysine, N-(N-acetylmuramoyl)-<smallcap>L</smallcap>-alanyl-<smallcap>D</span>-α-glutaminyl-N⁶-(1-oxooctadecyl)-, <span class="text-smallcaps">L</smallcap>-Lysine, N²-[N²-[N-(N-acetylmuramoyl)-<smallcap>L</smallcap>-alanyl]-<smallcap>D</span>-α-glutaminyl]-N⁶-(1-oxooctadecyl)-, Ac-Muramyl-Ala-D-Glu(Lys(Stearoyl)-Oh)-Nh2, Dj 7041, Muroctasin, Muroctasine, N-(N-Acetylmuramoyl)-<span class="text-smallcaps">L</smallcap>-alanyl-<smallcap>D</smallcap>-α-glutaminyl-N⁶-(1-oxooctadecyl)-<smallcap>L</span>-lysine, N^α-Acetylmuramoyl-<span class="text-smallcaps">L</smallcap>-alanyl-<smallcap>D</smallcap>-isoglutaminyl-N^ε-stearoyl-<smallcap>L</span>-lysine, Nopia, Romurtide
• CAS: 78113-36-7

Beschreibung

The investigation of the adjuvant activity of this muramyl peptide on humoral and cellular immune responses showed that it augments the mitogenic responses of splenic lymphocytes to phytohemagglutinin and lipopolysaccharide and the formation of antibodies to sheep erythrocytes in mice. In addition, it potentiated polyclonal B cell activation in vivo and in vitro.

• Marke: Bachem

Chemische Eigenschaften

• Molekulargewicht: 887.13
• Formel: C₄₃H₇₈N₆O₁₃
• Reinheit: > 98%
• Farbe/Form: White Powder