α-Synuclein (61-95) (human)

CAS: 154040-19-4

Ref. 01-4026207

Produktinformation

• Name: α-Synuclein (61-95) (human)
• Synonyme: Non-Aβ Component of Alzheimer's Disease Amyloid, Non-A.beta. Component of Alzheimers Disease Amyloid, H-Glu-Gln-Val-Thr-Asn-Val-Gly-Gly-Ala-Val-Val-Thr-Gly-Val-Thr-Ala-Val-Ala-Gln-Lys-Thr-Val-Glu-Gly-Ala-Gly-Ser-Ile-Ala-Ala-Ala-Thr-Gly-Phe-Val-OH
• CAS: 154040-19-4

Beschreibung

The 35 amino acid peptide NAC (a-synuclein (61-95)) has originally been isolated from the insoluble core of Alzheimer's disease (AD) amyloid plaque. The sequence corresponds to a fragment of a 140 amino acid precursor known as NACP or a-synuclein and was found to form amyloid fibrils via a nucleation-dependent polymerization mechanism. Accumulation of NAC aggregates in the synapse might be responsible for the neurodegeneration in AD and in the prion diseases.

• Marke: Bachem

Chemische Eigenschaften

• Molekulargewicht: 3260.65
• Formel: C₁₄₁H₂₃₅N₃₉O₄₉
• Reinheit: 84.7%
• Farbe/Form: White