Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH₂

CAS: 720710-69-0

Ref. 01-4028885

Produktinformation

• Name: Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH₂
• Synonyme: Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-Nh2, Mocac-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-Nh2

Beschreibung

The N-terminal elongation of the widely used MMP FRET substrate Mca-PLGL-Dpa-AR-NH₂ with a Lys yields a fluorogenic peptide with improved substrate properties. As compared to Mca-PLGL-Dpa-AR-NH₂, the specificity constant (kcat/Km) of the broad-spectrum MMP-substrate Mca-KPLGL-Dpa-AR-NH₂ for collagenases (MMP-1, MMP-8, MMP-13) and MMP-14 is increased two- to ninefold and threefold, respectively, while those for gelatinases and matrilysin remain equally high.

• Marke: Bachem

Chemische Eigenschaften

• Molekulargewicht: 1221.34
• Formel: C₅₅H₈₀N₁₆O₁₆
• Reinheit: 99.0%
• Farbe/Form: Yellow Lyophilisate