Apelin-13 (human, bovine, mouse, rat)

CAS: 217082-58-1

Ref. 01-4029109

Produktinformation

• Name: Apelin-13 (human, bovine, mouse, rat)
• Synonyme: 15: PN: WO2004081198 SEQID: 4 claimedsequence, 1: PN: WO2009033784 PAGE: 98 claimed protein, 2: PN:WO2009033819 PAGE: 103 claimed protein, 65-77-Apelin (Mus musculus), 65-77-Apelin, prepro-, Apelin-13, Gln-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe

Beschreibung

Apelin-13, generated from apelin-36, is an endogenous peptide ligand for the human APJ receptor, a putative receptor protein related to the angiotensin receptor (AT1). Apelin-13 exerted an acidification-rate-promoting activity in the CHO cells expressing the APJ receptor with a median effective concentration (EC₅₀) value of 0.37 nM. In a study of Valle et al. chronic central administration of apelin-13 over 10 days increased food intake, body weight, locomotor activity and body temperature in C57BL/6 mice.

• Marke: Bachem

Chemische Eigenschaften

• Molekulargewicht: 1550.85
• Formel: C₆₉H₁₁₁N₂₃O₁₆S
• Reinheit: 98.1%
• Farbe/Form: White White Lyophilisate