Cyclo(-Ala-Arg-Gly-Asp-3-aminomethylbenzoyl)

CAS: 153381-95-4

Ref. 01-4029366

Produktinformation

• Name: Cyclo(-Ala-Arg-Gly-Asp-3-aminomethylbenzoyl)
• Synonyme: XJ735, Cyclo(-Ala-Arg-Gly-Asp-3-Aminomethylbenzoyl) Tfa, Cyclo(-Ala-Arg-Gly-Asp-3-Aminomethylbenzoyl) Trifluoroacetate Salt, Xj735 Trifluoroacetate Salt, Cyclo(Ala-Arg-Gly-Asp-3-Aminomethyl-*Benzoyl)Triflu, Cyclo(Ala-Arg-Gly-Asp-3-Aminomethylbenzoyl)

Beschreibung

The small molecule RGD peptidomimetic αvβ3 integrin antagonist XJ-735 contains both anionic and cationic binding sites that straddle the RGD binding domain of the αvβ3 integrin. The IC₅₀ values of XJ 735 for αvβ3-mediated inhibition of human and porcine cell adhesion, and vascular smooth muscle cell migration, ranged from 0.6 to 4.4 µM. In contrast, IC₅₀ for porcine or human αIIb/β3, α4β1, αvβ5, and α5β1 inhibition exceeded 100 µM.

• Marke: Bachem

Chemische Eigenschaften

• Molekulargewicht: 532.56
• Formel: C₂₃H₃₂N₈O₇
• Reinheit: 97.2%