DABCYL-γ-Abu-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-EDANS

CAS: 127134-13-8

Ref. 01-4030716

Produktinformation

• Name: DABCYL-γ-Abu-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-EDANS
• Synonyme: 4-(4-Dimethylaminophenylazo)Benzoyl-Gamma-Abu-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-5-[(2-Aminoethyl)Amino]-Naphthalene-1-Sulfonic Acid, Hiv Protease Fret Substrate I, Dabcyl-Gaba-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Edans
• CAS: 127134-13-8

Beschreibung

The fluorogenic HIV-1 protease substrate DABCYL-Gaba-SQNYPIVQ-EDANS consists of an octapeptide with a fluorescent donor (EDANS) and a quenching acceptor (DABCYL), attached at the COOH- and NH2-termini. The g-Abu spacer was inserted to avoid potential steric hindrance of substrate binding by the bulky acceptor. This FRET substrate is cleaved by the HIV-1 protease at the Tyr-Pro bond which results in a time-dependent increase in fluorescence intensity; excitation at 340 nm, emission at 490 nm.

• Marke: Bachem

Chemische Eigenschaften

• Molekulargewicht: 1532.74
• Formel: C₇₃H₉₇N₁₇O₁₈S
• Reinheit: > 95%