Margatoxin

Ref. 01-4030845

Produktinformation

• Name: Margatoxin
• Marke: Bachem
• Beschreibung: Margatoxin (MgTX), originally isolated from the venom of the scorpion Centruroides margaritatus, is a peptidyl inhibitor of voltage dependent K⁺ channels in brain synaptic plasma membranes. MgTX blocks the n-type current of human T-lymphocytes (IC₅₀ = 50 pM, 20 fold more potent than charybdotoxin), has a lower dissociation rate and has no effect on Ca²⁺ activated channels. MgTX is therefore a useful tool to study the physiologic role of K⁺ channels.

Chemische Eigenschaften

• Molekulargewicht: 4179.01
• Formel: C₁₇₈H₂₈₆N₅₂O₅₀S₇
• Farbe/Form: Whitish Powder