TRAP-14

CAS: 137339-65-2

Ref. 01-4031275

Produktinformation

• Name: TRAP-14
• Synonyme: PAR-1 (1-14) (human), Ser-Phe-Leu-Leu-Arg-Asn-Pro-Asn-Asp-Lys-Tyr-Glu-Pro-Phe
• CAS: 137339-65-2

Beschreibung

Cloning and expression of a functional human thrombin receptor have revealed a protein with seven transmembrane domains and a large extracellular amino-terminal extension. Thrombin cleaves within this extension, thereby creating a new receptor amino-terminus that functions as a tethered ligand and activates the receptor. A 14-amino acid peptide mimicking this new amino-terminus has been found to be a potent thrombin receptor activator as well as an effective agonist for platelet activation.

• Marke: Bachem

Chemische Eigenschaften

• Molekulargewicht: 1739.95
• Formel: C₈₁H₁₁₈N₂₀O₂₃
• Reinheit: 98.1%
• Farbe/Form: White