PyBOP

CAS: 128625-52-5

Ref. 01-4031604

Produktinformation

• Name: PyBOP
• Synonyme: (1-Hydroxy-1H-benzotriazolato-O)tri-1-pyrrolidinylphosphorus(1+) hexafluorophosphate(1-), 1-Benzotriazolyloxytripyrrolidinylphosphonium hexafluorophosphate, 1H-Benzotriazol-1-yloxytripyrrolidinophosphonium Hexafluorophosphate, 1H-Benzotriazole, 1-hydroxy-, phosphorus complex, Benzotriazol-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate, Benzotriazol-1-yloxytripyrrolidinophosphonium hexafluorophosphate, Benzotriazole-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate, Phosphorus(1+), [1-(hydroxy-κO)-1H-benzotriazolato]tri-1-pyrrolidinyl-, (T-4)-, hexafluorophosphate(1-) (1:1), Pyrrolidine, phosphorus complex
• CAS: 128625-52-5

Beschreibung

A trademark of Merck KGaA, Darmstadt, Germany PyBOP is a well-established, effective coupling reagent. It has been developed to replace BOP which generates the carcinogenic HMPT as a by-product during coupling. Contrary to activation with uronium/aminium-type coupling reagents, by-products resulting from guanidinylation of the amino group cannot be formed. PyBOP has been used as well for obtaining peptide thioesters.

• Marke: Bachem

Chemische Eigenschaften

• Molekulargewicht: 520.4
• Formel: C₁₈H₂₈N₆OP·PF₆
• Farbe/Form: White