Fmoc-Asp(OtBu)-(Hmb)Gly-OH

CAS: 502640-94-0

Ref. 01-4035481

Produktinformation

• Name: Fmoc-Asp(OtBu)-(Hmb)Gly-OH
• Synonyme: Fmoc-Asp(OtBu)-N-(2-hydroxy-4-methoxy-Bzl)-Gly-OH, Fmoc-Asp(Otbu)-(Hmb)Gly-Oh, Fmoc-Asp(Otbu)-N-(2-Hydroxy-4-Methoxy-Bzl)-Gly-Oh, Fmoc-Asp(OtBu)-N(Hmb)-Gly-OH
• CAS: 502640-94-0

Beschreibung

Aspartimide formation of the highly base-labile Asp-Gly motif during Fmoc-SPPS may be completely suppressed by coupling this Hmb-protected dipeptide derivative. Additionally, Hmb prevents aggregation of the growing peptide chain as efficiently as the incorporation of a pseudoproline moiety. O-Acylation renders the Hmb moiety acid-stable facilitating the purification of peptides prone to form aggregates. The acyl group can be removed with hydrazine hydrate in DMF (cf. Quibell).

• Marke: Bachem

Chemische Eigenschaften

• Molekulargewicht: 604.67
• Formel: C₃₃H₃₆N₂O₉
• Reinheit: 99.6%
• Farbe/Form: White