GLP-1 (1-37) (human, bovine, guinea pig, mouse, rat)

CAS: 87805-34-3

Ref. 01-4037542

Produktinformation

• Name: GLP-1 (1-37) (human, bovine, guinea pig, mouse, rat)
• Synonyme: Proglucagon (72-108) (human, bovine, guinea pig, mouse, rat), Glucagon-like peptide I (1-37), Glp-I (1-37), Glucagon-related peptide I (ox), Glycine, L-histidyl-L-alpha-aspartyl-L-alpha-glutamyl-L-phenylalanyl-L-alpha-glutamyl-L-arginyl-L-histidyl-L-alanyl-L-alpha-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-alpha-aspartyl-L-valyl-L-seryl-L-seryl-L-tyrosyl-L-leucyl-L-alpha-glutamylglycyl-L-glutaminyl-L-alanyl-L-alanyl-L-lysyl-L-alpha-glutamyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-tryptophyl-L-leucyl-L-valyl-Llysylglycyl-L-arginyl-, Glp-1

Beschreibung

Glucagon-Like Peptide 1 (GLP-1) is synthesized by posttranslational processing of proglucagon in the intestine and pancreas and plays an important role in metabolic homeostasis. Among the different molecular forms, such as GLP-1 (7-36) amide and GLP-1 (7-37), the function of GLP-1 (1-37) has been unclear. GLP-1 (1-37) was shown to convert intestinal epithelial cells into insulin-producing cells. These observations turned GLP-1 (1-37) into a new promising therapeutic compound for the treatment of diabetes mellitus. In animal models of dilated cardiomyopathy, hypertensive heart failure, and myocardial infarction, GLP-1 has shown a remarkable cardioprotective activity.

• Marke: Bachem

Chemische Eigenschaften

• Molekulargewicht: 4169.54
• Formel: C₁₈₆H₂₇₅N₅₁O₅₉
• Reinheit: 97.1%
• Farbe/Form: White Lyophilisate