Endothelin-1 (human, bovine, dog, mouse, porcine, rat)

CAS: 117399-94-7

Ref. 01-4040254

Produktinformation

• Name: Endothelin-1 (human, bovine, dog, mouse, porcine, rat)
• Synonyme: ET-1 (human, bovine, dog, mouse, porcine, rat), Endothelin 1 human, porcine, H-Cys-Ser-Cys-Ser-Ser-Leu-Met-Asp-Lys-Glu-Cys-Val-Tyr-Phe-Cys-His-Leu-Asp-Ile-Ile-Trp-OH (Disulfide bonds between Cys1 and Cys15/Cys3 and Cys11), Endothelin 1, Human and Porcine, Endothelin-1,Human, Endothelin-1 (human, bovine, dog, mouse, porcine, rat) acetate salt

Beschreibung

Endothelin-1, a 21-amino acid peptide from vascular endothelial cells of different mammalian species, is one of the most potent vasoconstrictors. ET-1 exerts a wide variety of effects on both vascular and non-vascular (e.g. heart, lung, brain) tissues. Toxic peptides from a snake venom, the sarafotoxins, show structural and functional homology to ET-1. The role of ET-1 in clinical hypertension has been reviewed by Dhaun et al. and by Sreenivas and Oparil. ET-1 plays a central role in lung fibrosis.

• Marke: Bachem

Chemische Eigenschaften

• Molekulargewicht: 2491.94
• Formel: C₁₀₉H₁₅₉N₂₅O₃₂S₅
• Reinheit: 91.90%
• Farbe/Form: White