Galanin-Like Peptide (rat)

CAS: 245114-97-0

Ref. 01-4047028

Produktinformation

• Name: Galanin-Like Peptide (rat)
• Synonyme: GALP (rat), 16: PN:WO0177166 SEQID: 15 claimed protein, 2: PN: JP2000270871 SEQID: 2 claimedprotein, GALP (Rattus norvegicus), GALP (galanin-like peptide) (rathypothalamus), PN: WO9948920 SEQID: 33 claimed protein, Peptide (rat 60-aminoacid), Galanin-Like Peptide (Rat)

Beschreibung

Galanin-like peptide (GALP), first isolated from the porcine hypothalamus and subsequently also identified in rats and humans, is a 60 amino acid neuropeptide that unlike galanin, has a non-amidated C-terminus. Its amino acid residues (9-21) are identical to the biologically active N-terminal (1-13) fragment of galanin. In contrast to galanin which is relatively non-selective, receptor binding studies revealed that GALP had a high affinity for the galanin receptor 2 (GALR2) and a lower affinity for the GALR1 receptor. Furthermore, it could be demonstrated that GALP stimulates food intake with a ten fold higher orexigenic activity than galanin and may also affect emotional state in the CNS.

• Marke: Bachem

Chemische Eigenschaften

• Molekulargewicht: 6502.43
• Formel: C₂₈₈H₄₆₁N₈₇O₈₃S
• Reinheit: > 95%
• Farbe/Form: White Powder