FSL-1-DYKDDDDK

CAS: 2243206-97-3

Ref. 01-4099727

Produktinformation

• Name: FSL-1-DYKDDDDK
• Synonyme: Fibroblast Stimulating Lipopeptide 1 FLAG-tag
• Marke: Bachem
• Beschreibung: The lipopeptide FSL-1, synthesized on the basis of the N-terminal structure of a M. salivarium lipoprotein, is capable of inducing the cell surface expression of ICAM-1 in human gingival fibroblasts. It furthermore revealed an activity to induce production of monocyte chemoattractant protein 1, interleukin-6 (IL-6), and IL-8. FSL-1 also activated macrophages to produce tumor necrosis factor alpha. Overall, results by Okusawa and coworkers suggest that the diacylglyceryl and the peptide portions of FSL-1 are indispensable for the expression of biological activities and for the recognition by Toll-like receptors 2 and 6. Furthermore, the same authors conclude that the recognition of FSL-1 by Toll-like receptors 2 and 6 apparently is hydrophobic.

Chemische Eigenschaften

• Molekulargewicht: 2661.15
• Formel: C₁₂₅H₁₉₈N₂₄O₃₇S
• Reinheit: 97.0%
• Farbe/Form: White Powder