4-Bromobenzonitrile, 98+%

CAS: 623-00-7

Ref. 02-A10914

Produktinformation

• Name: 4-Bromobenzonitrile, 98+%
• Synonyme: 4-Cyanobromobenzene, 1-Bromo-4-benzonitrile, 1-Bromo-4-cyanobenzene, 1-Cyano-4-bromobenzene, 4-Bormobenzonitrile, 4-Brombenzonitril, 4-Bromo-Benzonitril, 4-Bromobenzenitrile, 4-Bromobenzoic Acid Nitrile, 4-Bromobenzonitrilo, 4-Bromocyanobenzene, 4-Bromophenyl cyanide, 4-Bromophenylcarbonitrile, 4-Cyano-1-bromobenzene, 4-Cyanophenyl bromide, Benzonitrile, 4-bromo-, Benzonitrile, p-bromo-, Bromobenzonitrile-4, Nsc 3978, P-Bromobenzonitrile, Pbbn, p-Bromocyanobenzene, p-Bromophenyl cyanide, p-Cyanobromobenzene, p-Cyanophenyl bromide

Beschreibung

4-Bromobenzonitrile is used as reagents and solvents. Reaction of 2-propanol, 4-bromobenzonitrile, and NaH in the presence of 1.5 mol % Pd2(dba)3 and 3 mol % (S)-(-)2,2?-bis(di-p-tolylphosphino)- 1,1?-binaphthyl at 50°C afforded 4-isopropoxy- benzonitrile in 80% isolated yield. The synthesis of 4-cyanobiphenyl at room temperature in a flow injection microreactor, using a supported catalyst, without the addition of a base gave a product yield of 67±7% (n=6). This was achieved by injecting 4-bromobenzonitrile. The 3-arylation of 2,5-dimethylthiophene with 4-bromopropiophenone, 4-trifluoromethylbromobenzene or 4-bromobenzonitrile gave 3-5 in only 38-50% yields in Palladium-catalysed direct 3-or 4-arylation of thiophene derivatives using aryl bromides.This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

• Marke: Alfa Aesar By Thermo Fisher Scientific

Chemische Eigenschaften

• Molekulargewicht: 182.03
• Formel: C₇H₄BrN
• Reinheit: 98+%
• Farbe/Form: Crystalline powder or flakes, White to pale cream or pale yellow
• InChl: InChI=1S/H3N/h1H3
• InChI Key: InChIKey=QGZKDVFQNNGYKY-UHFFFAOYSA-N
• SMILES: N#Cc1ccc(Br)cc1