Phenoxyacetyl chloride, 98%

CAS: 701-99-5

Ref. 02-A13761

Produktinformation

• Name: Phenoxyacetyl chloride, 98%
• Synonyme: 2-phenoxyacetyl chloride, 2-Phenoxyacetyl chloride, Acetyl chloride, 2-phenoxy-, Acetyl chloride, phenoxy-, Acetylchloride,phenoxy-, Acyl chloride kind, Akos Bbs-00003927, Chlorure de phenoxyacetyle, Cloruro De Fenoxiacetilo, Labotest-Bb Lt00643586, Nsc 9808, Phenoxy-Acetylchlorid, Phenoxyacetic acid chloride, Phenoxyacetylchlorid, Phenoxyethanoyl chloride, Phenyloxyacetyl chloride

Beschreibung

Acylation of D- and DL-WV with phenoxyacetyl chloride, followed by cleavage of the t-butyl ester,afforded the penultimate penicilloic acids. Phenoxyacetyl chloride was used in the synthesis of series of macrocyclic bis-β-lactams, 5-phenyl-6-epiphenoxymethylpenicillin benzyl ester, N-protected guanosine derivatives, useful in RNA synthesis, phenyloxyketene, for cycloaddition to imines leading to β-lactams. Treatment of iminophosphoranes with phenoxyacetyl chloride afforded respectively the trans- and cis-3-(acylamino)-p-lactams. By the oxidative addition of stannous fluoride to allyliodide, with 1, 2-O-isopropylidene-D-glyceraldehyde and phenoxyacetyl chloride results in the predominant formation of erythro homoallylester, which is in turn converted into 2-deoxy-D-ribose. The 4-disubstituted P-lactams (4a-c and 6a-b) were prepared through the reaction of N,N-diphenylhydrazones and N-methyl-N-phenylhydrazones of ketones with phenoxyacetyl chloride/Et3N in dichloromethane. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

• Marke: Alfa Aesar By Thermo Fisher Scientific

Chemische Eigenschaften

• Molekulargewicht: 170.59
• Formel: C₈H₇ClO₂
• Reinheit: 98%
• Farbe/Form: Liquid, Clear colorless to yellow to brown
• InChl: InChI=1S/C8H7ClO2/c9-8(10)6-11-7-4-2-1-3-5-7/h1-5H,6H2
• InChI Key: PKUPAJQAJXVUEK-UHFFFAOYSA-N
• SMILES: O=C(Cl)COc1ccccc1