4-Thiouridine, 98+%

CAS: 13957-31-8

Ref. 02-J60679

Produktinformation

• Name: 4-Thiouridine, 98+%
• Synonyme: 1-beta-D-ribofuranosyl-4-thioxo-3,4-dihydropyrimidin-2(1H)-one, 1-pentofuranosyl-4-thioxo-3,4-dihydropyrimidin-2(1H)-one, Nsc 518132, Thiouridine, Thiouridine (VAN), Uridine, 4-thio-

Beschreibung

4-Thiouridine is a constituent of several transfer RNA's. 4-Thiouridine is a thionucleobase used as an antisense agent. Widely used for RNA analysis including RNA-RNA cross coupling and RNA labelling. 4-Thiouridine is a photoreactive (crosslinking) uridine analogue that upon phosphorylation to 4-thioUTP may be incorporated into RNA structures. 4-Thiouridine may be used to study the specificity and kinetics of uridine-cytidine kinases. 4-Thio Uridine is typically used to modify oligos slated for RNA, or RNA-protein, structural studies. A 4-thio-rU modified RNA pentamer was used to study the effect of this modification on codon-anticodon interaction when it is in the wobble position of tRNA. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

• Marke: Alfa Aesar By Thermo Fisher Scientific

Chemische Eigenschaften

• Molekulargewicht: 260.27
• Formel: C₉H₁₂N₂O₅S
• Reinheit: 98+%
• Farbe/Form: Off-white to pale yellow, Powder