CGS 21680 hydrochloride, 99%

CAS: 120225-54-9

Ref. 02-J60793

Produktinformation

• Name: CGS 21680 hydrochloride, 99%
• Synonyme: 2-[4-(2-Carboxyethyl)phenylethylamino]-5'-(N-ethyl)carboxamidoadenosine, 3-{4-[2-({6-amino-9-[(3R,4S,5S)-5-(ethylcarbamoyl)-3,4-dihydroxytetrahydrofuran-2-yl]-9H-purin-2-yl}amino)ethyl]phenyl}propanoic acid (non-preferred name), 4-[2-[[6-Amino-9-(N-ethyl-β-<span class="text-smallcaps">D</span>-ribofuranuronamidosyl)-9H-purin-2-yl]amino]ethyl]benzenepropanoic acid, Benzenepropanoic acid, 4-[2-[[6-amino-9-(N-ethyl-β-<span class="text-smallcaps">D</span>-ribofuranuronamidosyl)-9H-purin-2-yl]amino]ethyl]-, Cgs-21680

Beschreibung

CGS 21680 hydrochloride is currently used in research in studying neuronal transmission, also in respiration. CGS 21680 is commonly used to study the actions of the adenosine A2A receptor in cells and tissues. CGS 21680 HCl is an adenosine A2 receptor agonist with IC50 of 22 nM, exhibits 140-fold over A1 receptor. CGS 21680C effectively increases coronary flow with an ED25 value of 1.8 nM. In hippocampal slices, CGS 21680 apis weak agonist on pre- and postsynaptic measures of electrophysiologicaJ activity. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

• Marke: Alfa Aesar By Thermo Fisher Scientific

Chemische Eigenschaften

• Molekulargewicht: 535.98
• Formel: C₂₃H₂₉N₇O₆•HCl
• Reinheit: 99%
• Farbe/Form: White Solid