dehydroergosterol (DHE)

CAS: 516-85-8

Ref. 3D-AAA51685

Produktinformation

• Name: dehydroergosterol (DHE)
• Synonyme: (22E)-Ergosta-5,7,9(11),22-tetraen-3β-ol, (22E,24R)-Ergosta-5,7,9(11),22-tetraen-3β-ol, (3beta,22E)-ergosta-5,7,9(11),22-tetraen-3-ol, (3β,22E)-Ergosta-5,7,9(11),22-tetraen-3-ol, 9(11)-Dehydroergosterol, Dehydroergosterol, Ergosta-5,7,9(11),22-Tetraen-3-Beta-Ol, Ergosta-5,7,9(11),22-tetraen-3-ol, (3β,22E)-, Ergosta-5,7,9(11),22-tetraenol

Beschreibung

Dehydroergosterol, also known as DHE, is a cholesterol derivative that is a pro-apoptotic protein. It has been shown to inhibit the proliferation of cancer cells by binding to the ATP-binding cassette transporter and MCL-1 protein. DHE binds to cholesterol and changes its phase transition temperature from liquid to solid at physiological levels, which may be due to its anti-cancer properties. The pro-apoptotic effect of DHE was demonstrated in a model system using skin cancer cells. This compound also has been shown to have anti-cancer activity against colorectal adenocarcinoma cells in vitro and in vivo.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 394.63 g/mol
• Formel: C₂₈H₄₂O
• Reinheit: Min. 95%