2-Hydroxy-5-nitrobenzohydrazide

CAS: 946-32-7

Ref. 3D-AAA94632

Produktinformation

• Name: 2-Hydroxy-5-nitrobenzohydrazide
• Synonyme: Benzoic acid, 2-hydroxy-5-nitro-, hydrazide, 2-Hydroxy-5-nitrobenzoic acid hydrazide, Salicylic acid, 5-nitro-, hydrazide, (2-Hydroxy-5-nitrobenzoyl)hydrazine, 5-Nitrosalicyl hydrazide

Beschreibung

2-Hydroxy-5-nitrobenzohydrazide is an antibacterial agent that binds to the hydroxylase domain of bacterial 7-ethoxycoumarin hydroxylase, a key enzyme in the synthesis of tetranuclear cofactors. It forms a coordination geometry with the metal ions that are required for this enzyme, thereby blocking its activity. 2-Hydroxy-5-nitrobenzohydrazide has been shown to be effective against bacteria such as Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa. This compound also has a specific affinity for mononuclear bacteria such as Proteus mirabilis and Klebsiella pneumoniae.
2-Hydroxy-5-nitrobenzohydrazide is not active against Gram positive bacteria due to its lack of binding affinity for the epoxide hydrolase domain of bacterial 7-ethoxycou

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 197.15 g/mol
• Formel: C₇H₇N₃O₄
• Reinheit: Min. 95%