Bicozamycin

CAS: 38129-37-2

Ref. 3D-AB61701

Produktinformation

• Name: Bicozamycin
• Synonyme: Aizumycin, (1S,6R)-6-Hydroxy-5-methylene-1-[(1S,2S)-1,2,3-trihydroxy-2-methylpropyl]-2-oxa-7,9-diazabicyclo[4.2.2]decane-8,10-dione, (1S,6R)-6-hydroxy-5-methylene-1-(1,2,3-trihydroxy-2-methyl-propyl)-2-oxa-7,9-diazabicyclo[4.2.2]decane-8,10-dione, (1S,6R)-6-hydroxy-5-methylidene-1-[(1S,2S)-1,2,3-trihydroxy-2-methylpropyl]-2-oxa-7,9-diazabicyclo[4.2.2]decane-8,10-dione, 2-Oxa-7,9-diazabicyclo[4.2.2]decane, bicyclomycin deriv., 2-Oxa-7,9-diazabicyclo[4.2.2]decane-8,10-dione, 6-hydroxy-5-methylene-1-(1,2,3-trihydroxy-2-methylpropyl)-, [1S-[1α,1(1R*,2R*),6β]]-, 2-Oxa-7,9-diazabicyclo[4.2.2]decane-8,10-dione, 6-hydroxy-5-methylene-1-[(1S,2S)-1,2,3-trihydroxy-2-methylpropyl]-, (1S,6R)-, 6-Hydroxy-5-Methylidene-1-(1,2,3-Trihydroxy-2-Methylpropyl)-2-Oxa-7,9-Diazabicyclo[4.2.2]Decane-8,10-Dione, Antibiotic 5879, Antibiotic WS 4545, Bicyclomycin, [1S-[1α,1(1R*,2R*),6β]]-6-Hydroxy-5-methylene-1-(1,2,3-trihydroxy-2-methylpropyl)-2-oxa-7,9-diazabicyclo[4.2.2]decane-8,10-dione

Beschreibung

Bicozamycin is a drug that belongs to the group of antimicrobial agents. It has been shown to inhibit the growth of c. glabrata and other infectious bacteria. Bicozamycin binds to bacterial RNA polymerase, preventing transcription and replication. This binding prevents the formation of an antibiotic-inhibitor complex with the enzyme cell wall synthesis that is required for cell wall biosynthesis, inhibiting protein synthesis and cell division. Bicozamycin also inhibits drug transporter proteins in human cells and has been shown to be effective against resistant mutants in vitro.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 302.28 g/mol
• Formel: C₁₂H₁₈N₂O₇
• Reinheit: (Hplc-Ms) Min. 90 Area-%
• Farbe/Form: Powder