Amyloid β-Protein (Human, 1-42) (Scrambled)

Ref. 3D-ABP-4514-S

Produktinformation

• Name: Amyloid β-Protein (Human, 1-42) (Scrambled)
• Marke: Biosynth
• Beschreibung: Amyloid beta-protein (Aβ) is a peptide that is involved in the pathogenesis of Alzheimer's disease. The protein is a type of amyloid, and it consists of 39-43 amino acid residues. It was originally discovered as a component of the amyloid plaques that are found in the brains of patients with Alzheimer's disease. Aβ is derived from sequential cleavage by enzymes including β-secretase and γ-secretase, which generate a linear peptide composed of residues 1-42. Cleavage by α-secretase prevents production of Aβ. The linear form can be converted to an insoluble form (amyloid fibrils) through sequential exposure to β- or γ- secretases, or to soluble oligomers (Aβ*). These transformations are thought to be involved in the development and progression of Alzheimer's disease. Amyloid beta protein (1-42) has been shown to bind with high affinity to

Chemische Eigenschaften

• Reinheit: Min. 95%