Cefacetrile sodium

CAS: 23239-41-0

Ref. 3D-AC45119

Produktinformation

• Name: Cefacetrile sodium
• Synonyme: 23239-41-0, 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[(acetyloxy)methyl]-7-[(2-cyanoacetyl)amino]-8-oxo-, sodium salt (1:1), (6R,7R)-, 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[(acetyloxy)methyl]-7-[(cyanoacetyl)amino]-8-oxo-, monosodium salt, (6R,7R)-, 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[(acetyloxy)methyl]-7-[(cyanoacetyl)amino]-8-oxo-, monosodium salt, (6R-trans)-, 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-(2-cyanoacetamido)-3-(hydroxymethyl)-8-oxo-, acetate (ester), monosodium salt, 7-Cyanoacetylaminocephalosporanic acid sodium salt, Ba 36278, CIBA 36278Ba, Celospor, Celtol, Cephacetrile sodium, Cephacetrile-Na, Masticef, Sodium 3-(acetoxymethyl)-7-(2-cyanoacetamido)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate, Sodium 7-(2-cyanoacetamido)cephalosporanic acid, Sodium 7-cyanacetamidocephalosporanate, Sodium cefacetril, Sodium cefacetrile, Sodium cephacetrile, Vetimast, sodium (6R,7R)-3-[(acetyloxy)methyl]-7-[(cyanoacetyl)amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate, sodium (6S,7S)-3-[(acetyloxy)methyl]-7-[(cyanoacetyl)amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

Beschreibung

Cefacetrile sodium is a low-potency, chemically stable, broad-spectrum antimicrobial agent that is active against gram-positive bacteria. It has been shown to bind to penicillin-binding proteins in the bacterial cell wall by competitive inhibition. This binding prevents the formation of an antibiotic-inhibitor complex with the enzyme cell wall synthesis that is required for cell wall biosynthesis, inhibiting protein synthesis and cell division. Cefacetrile sodium also has low solubility in water, which makes it difficult to administer orally. The drug may be administered intravenously or intramuscularly as an injection or taken by mouth as a tablet or suspension.
Cefacetrile sodium was developed for the treatment of urinary tract infections (UTIs) caused by Escherichia coli, Proteus mirabilis, and Enterobacter cloacae. It has been shown to have bacteriostatic activity against these bacteria at concentrations up to

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 362.31 g/mol
• Formel: C₁₃H₁₃N₃NaO₆S
• Reinheit: Min. 95%