2'-Deoxycoformycin
CAS: 53910-25-1
Ref. 3D-AD03945
1mg | 197,00 € | ||
2mg | 307,00 € | ||
5mg | 400,00 € | ||
10mg | 569,00 € | ||
25mg | 949,00 € |
Produktinformation
- pentostatin
- (8R)-3-(2-Deoxy-β-<span class="text-smallcaps">D</span>-erythro-pentofuranosyl)-3,4,7,8-tetrahydroimidazo[4,5-d][1,3]diazepin-8-ol
- (8R)-3-(2-deoxy-beta-D-erythro-pentofuranosyl)-3,4,7,8-tetrahydroimidazo[4,5-d][1,3]diazepin-8-ol
- (8R)-3-[(4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-7,8-dihydro-4H-imidazo[4,5-f][1,3]diazepin-8-ol
- (R)-3-(2-Deoxy-Beta-D-Erythro-Pento-Furanosyl)-3,6,7,8-Tetrahydroimidazo[4,5-D
- (R)-3-(2-Deoxy-Beta-D-Pentofuranosyl)-3,6,7,8-Tetrahydroimidazo(4,5-D)(1,3)D
- (R)-Deoxycoformycin
- (R)-Rahydro
- 2'-Dcf
- 2'-Dexoycoformycin
- Mehr Synonyme anzeigen
- 2’-Deoxycoformycin
- 2’Dcf
- Ci-825
- Cl 67310465
- Cl 825
- Co-V
- Co-Vidarabine
- Coforin
- Deaminase inhibitor
- Deoxycoformycin
- Imidazo[4,5-d][1,3]diazepin-8-ol, 3-(2-deoxy-β-<span class="text-smallcaps">D</span>-erythro-pentofuranosyl)-3,4,7,8-tetrahydro-, (8R)-
- Imidazo[4,5-d][1,3]diazepin-8-ol, 3-(2-deoxy-β-<span class="text-smallcaps">D</span>-erythro-pentofuranosyl)-3,4,7,8-tetrahydro-, (R)-
- Imidazo[4,5-d][1,3]diazepin-8-ol, 3-(2-deoxy-β-D-erythro-pentofuranosyl)-3,4,7,8-tetrahydro-, (8R)-
- Imidazo[4,5-d][1,3]diazepin-8-ol, 3-(2-deoxy-β-D-erythro-pentofuranosyl)-3,4,7,8-tetrahydro-, (R)-
- Nipent
- Nsc 218321
- Nsc 247520
- Pd-Adi
- Vira A deaminase inhibitor
2'-Deoxycoformycin is a drug that inhibits the synthesis of DNA, RNA, and proteins. It is an analog of coformycin which has been shown to be effective against congestive heart failure. 2'-Deoxycoformycin inhibits the surface glycoprotein on T-cells and also inhibits the proliferation of human T-cell lymphoma cells in culture. This drug has minimal toxicity and can be used to treat infectious diseases. 2'-Deoxycoformycin binds to the mcl-1 protein which regulates apoptosis, hematopoiesis, and inflammation. The drug may inhibit multidrug resistance by binding to a site that is not accessible to pentostatin or other nonsteroidal anti-inflammatory drugs. The drug has been shown to inhibit the growth of bowel disease in animals. 2'-Deoxycoformycin binds reversibly to DNA polymerase alpha or beta at concentrations that are 10 times lower than those needed for inhibition
Chemische Eigenschaften
Technische Anfrage zu: 3D-AD03945 2'-Deoxycoformycin
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