9-Deoxo-9a-aza-9a-homo erythromycin A

CAS: 76801-85-9

Ref. 3D-AD21039

Produktinformation

• Name: 9-Deoxo-9a-aza-9a-homo erythromycin A
• Synonyme: Azaerythromycin AAzathramycinDesmethylazithromycin, (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-13-[(2,6-Dideoxy-3-C-methyl-3-O-methyl-α-<span class="text-smallcaps">L</smallcap>-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-<smallcap>D</span>-xylo-hexopyranosyl]oxy]-1-oxa-6-azacyclopentadecan-15-one, 1-Oxa-6-azacyclopentadecan-15-one, 13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-<span class="text-smallcaps">L</smallcap>-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-<smallcap>D</span>-xylo-hexopyranosyl]oxy]-, (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-, 1-Oxa-6-azacyclopentadecan-15-one, 13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-<span class="text-smallcaps">L</smallcap>-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-<smallcap>D</span>-xylo-hexopyranosyl]oxy]-, [2R-(2R*,3S*,4R*,5R*,8R*,10R*,11R*,12S*,13S*,14R*)]-, 2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-15-oxo-11-{[3,4,6-trideoxy-3-(dimethylamino)hexopyranosyl]oxy}-1-oxa-6-azacyclopentadecan-13-yl 2,6-dideoxy-3-C-methyl-3-O-methylhexopyranoside, 9-Deoxo-9a-aza-9a-homoerythromycin A, Aza-erythromycin, Azaerythromycin A, Azahomoerythromycin, Desmethyl Azithromycin

Beschreibung

9-Deoxo-9a-aza-9a-homo erythromycin A is a semisynthetic derivative of erythromycin. It has been synthesized by using a template molecule that has been modified by replacing the 9-hydroxyl group with a 9-deoxy group. This precursor undergoes a series of reactions to yield 9-deoxo-9a-aza-9a-homo erythromycin A. The synthesis of this molecule was achieved in three steps, starting with an N-(2′,4′,6′)-trichloroacetimidate intermediate and ending with the desired product. 9DEOEA has shown antimicrobial efficacy against Gram positive bacteria such as Streptococcus pneumoniae, Enterococcus faecalis, and Staphylococcus epidermidis.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 734.96 g/mol
• Formel: C₃₇H₇₀N₂O₁₂
• Reinheit: Min. 90%
• Farbe/Form: White Powder