Temarotene

CAS: 75078-91-0

Ref. 3D-ADA07891

Produktinformation

• Name: Temarotene
• Marke: Biosynth
• Beschreibung: Temarotene is an all-trans retinoic acid (ATRA) analog that binds to the IL-2 receptor with high affinity and specificity. It has been shown to inhibit the proliferation of HL-60 cells in vitro, which may be due to its ability to induce the release of colony-stimulating factor from these cells. Temarotene also enhances the uptake of ATRA by HL-60 cells and increases the expression of receptors for ATRA in humans. In vivo studies have shown that temarotene is a potent inducer of fatty acid synthesis in Sprague-Dawley rats. This agent has a long half-life and is rapidly absorbed when administered orally, with peak plasma concentrations occurring 2 hours after administration. The pharmacokinetic properties of this drug are similar to those of other synthetic retinoids, such as all-trans-retinoic acid.

Chemische Eigenschaften

• Molekulargewicht: 304.5 g/mol
• Formel: C₂₃H₂₈
• Reinheit: Min. 95%