7-methyl-5-nitro-1H-indazole

CAS: 75785-12-5

Ref. 3D-ADA78512

Produktinformation

• Name: 7-methyl-5-nitro-1H-indazole
• Synonyme: 1H-Indazole, 7-methyl-5-nitro-, 7-Methyl-5-nitro-1H-indazole

Beschreibung

7-Methyl-5-nitro-1H-indazole is an analog of amodiaquine, a drug used in the treatment of malaria. The compound has been shown to be hepatotoxic, which may be due to its metabolic conversion to an amino group. 7-Methyl-5-nitro-1H-indazole inhibits the growth of malaria parasites by causing DNA damage and inhibition of protein synthesis. It is metabolized by hydroxylation and excreted as a stable metabolite. This drug has been shown to be potent against malarial parasites and has anti-malarial properties that are similar to those of amodiaquine.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 177.16 g/mol
• Formel: C₈H₇N₃O₂
• Reinheit: Min. 95%