4'-Epidaunorubicin hydrochloride

CAS: 56390-08-0

Ref. 3D-AE16714

Produktinformation

• Name: 4'-Epidaunorubicin hydrochloride
• Synonyme: (8S,10S)-8-Acetyl-10-[(3-amino-2,3,6-trideoxy-a-L-arabino-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-na phthacenedione hydrochloride(8S-cis)-4'-Epidaunorubicin hydrochloride4'-epi-daunomycin hydrochloride
• Marke: Biosynth
• Beschreibung: 4'-Epidaunorubicin hydrochloride is an anthracycline antibiotic derivative, which is synthesized from modifications of natural products. It functions as a topoisomerase II inhibitor, which intercalates into DNA strands and disrupts replication and transcription, thereby inhibiting cancer cell proliferation. This compound is primarily utilized in the field of oncology for its potent anti-tumor activities. By forming stable complexes with DNA and topoisomerase II, 4'-Epidaunorubicin hydrochloride induces breaks in the DNA strands, leading to apoptosis of cancer cells. It is often used in treatment protocols for various malignancies, including leukemia and solid tumors. While highly effective, its administration is carefully managed to mitigate potential cardiotoxicity, a common attribute of anthracycline drugs. Research continues to explore its full potential and optimize delivery methods to enhance its therapeutic index.

Chemische Eigenschaften

• Molekulargewicht: 563.98 g/mol
• Formel: C₂₇H₃₀ClNO₁₀
• Reinheit: Min. 95%