GS 441524

CAS: 1191237-69-0

Ref. 3D-AG167808

Produktinformation

• Name: GS 441524
• Synonyme: Aminopyrrolo[2,​1-​f]​[1,​2,​4]​triazin-​7-​yl)​-​2,​5-​anhydro-D-​altrononitrileRemdesivir Related Compound 6, (2R,3R,4S,5R)-2-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile
• CAS: 1191237-69-0

Beschreibung

Nucleoside analog with antiviral activity against zoonotic feline infectious peritonitis virus (FIPV) and severe acute respiratory syndrome (SARS) virus from Coronaviridae family. The compound is a pro-drug and undergoes intracellular phosphorylation resulting in the active triphosphate metabolite. The triphosphorylated GS 441524 analog competes with natural nucleoside triphosphates and interferes with viral RNA synthesis. In previous studies it was tested in vitro as well as in experimental animals and showed good safety profile.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 291.26 g/mol
• Formel: C₁₂H₁₃N₅O₄
• Reinheit: Min. 98 Area-%
• Farbe/Form: Powder