Orbifloxacin

CAS: 113617-63-3

Ref. 3D-AO40692

Produktinformation

• Name: Orbifloxacin
• Synonyme: 1-Cyclopropyl-5,6,8-trifluoro-1,4-dihydro-7-(cis-3,5-dimethyl-1-piperazinyl)-4-oxo-quinoline-3-carboxylic acid, 1-Cyclopropyl-7-[(3R,5S)-3,5-dimethylpiperazin-1-yl]-5,6,8-trifluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid, 3-Quinolinecarboxylic acid, 1-cyclopropyl-7-(3,5-dimethyl-1-piperazinyl)-5,6,8-trifluoro-1,4-dihydro-4-oxo-, cis-, 3-Quinolinecarboxylic acid, 1-cyclopropyl-7-[(3R,5S)-3,5-dimethyl-1-piperazinyl]-5,6,8-trifluoro-1,4-dihydro-4-oxo-, rel-, 3-quinolinecarboxylic acid, 1-cyclopropyl-7-[(3R,5S)-3,5-dimethyl-1-piperazinyl]-5,6,8-trifluoro-1,4-dihydro-4-oxo-, Cp 104354, Orbax, rel-1-Cyclopropyl-7-[(3R,5S)-3,5-dimethyl-1-piperazinyl]-5,6,8-trifluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid

Beschreibung

Orbifloxacin is a fluoroquinolone antibiotic that inhibits bacterial growth by inhibiting DNA gyrase and topoisomerase IV. It has been shown to be effective against methicillin-resistant Staphylococcus aureus (MRSA) and Clostridium perfringens, although is not active against acid-fast bacteria such as Mycobacterium tuberculosis or Mycobacterium avium complex. Orbifloxacin has shown anti-inflammatory properties, which may be due to its inhibition of prostaglandin synthesis. In vivo studies have demonstrated that orbifloxacin induces pro-apoptotic protein expression in necrotic cells via the activation of caspases 3, 9 and 3/7 pathways.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 395.38 g/mol
• Formel: C₁₉H₂₀F₃N₃O₃
• Reinheit: Min. 95%
• Farbe/Form: Powder