Phleomycin

CAS: 11006-33-0

Ref. 3D-AP106412

Produktinformation

• Name: Phleomycin
• Marke: Biosynth
• Beschreibung: Phleomycin is an antibiotic, which is derived from the bacterium *Streptomyces verticillus*. Its mode of action involves binding to DNA and inducing breaks by generating free radicals in the presence of oxygen and ferrous ions, leading to cell death. Phleomycin is prominently used in molecular biology applications as a selective agent in the generation of stable transfectants. It is particularly effective in selecting for cells that have integrated vectors conferring resistance, such as the Sh ble gene used in yeast, plant, and mammalian cell systems. Due to its potent DNA-cleaving ability, Phleomycin is valuable in studies requiring stringent selection pressure. Researchers commonly utilize it in experiments focusing on genetic modification and cellular resistance development.

Chemische Eigenschaften

• Molekulargewicht: 1,326.38 g/mol
• Formel: C₅₁H₇₅N₁₇O₂₁S₂
• Reinheit: Min. 95%