Apatinib

CAS: 811803-05-1

Ref. 3D-BA175030

Produktinformation

• Name: Apatinib
• Synonyme: 3-Pyridinecarboxamide, N-[4-(1-cyanocyclopentyl)phenyl]-2-[(4-pyridinylmethyl)amino]-, Apatinib (YN968D1), Apatinib mesylate, Aptinib, N-[4-(1-Cyanocyclopentyl)phenyl]-2-[(4-pyridinylmethyl)amino]-3-pyridinecarboxamide, N-[4-(1-cyanocyclopentyl)phenyl]-2-[(pyridin-4-ylmethyl)amino]pyridine-3-carboxamide, Rivoceranib, Yn 968D1, N-[4-(1-Cyanocyclopentyl)phenyl]-2-[(4-pyridinylmethyl)amino]pyridine-3-carboxamide

Beschreibung

Apatinib, also known as rivoceranib, is an inhibitor of the vascular endothelial growth factor receptor 2 (VEGFR2) tyrosine kinase. Apatinib targets VEGFR2 with its action and has proven to have strong anti-tumor effects in human cancers. In studies in mice, apatinib acted as an Inhibitor of VEGFR2 and played an antiangiogenic effect. Apatinib has been suggested for the treatment of ischemia-induced proliferative retinopathy and neovascular age-related macular degeneration.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 397.47 g/mol
• Formel: C₂₄H₂₃N₅O
• Reinheit: Min. 95%
• Farbe/Form: Powder