1-Methyl-5-nitro-1H-pyrrole-2-carboxylic acid

CAS: 1873-12-7

Ref. 3D-BAA87312

Produktinformation

• Name: 1-Methyl-5-nitro-1H-pyrrole-2-carboxylic acid

Beschreibung

1-Methyl-5-nitro-1H-pyrrole-2-carboxylic acid is a synthetic, nonpeptide antiviral agent that inhibits coxsackie virus and other enteroviruses. It is structurally related to the nucleoside analogues of acyclovir and ganciclovir. 1-Methyl-5-nitro-1H-pyrrole-2-carboxylic acid binds to the viral RNA genome in a sequence specific manner. This binding prevents the synthesis of viral proteins, which results in inhibition of virus replication. 1MPA has been shown to inhibit the growth of tumor cell lines in vitro and in vivo, as well as murine leukemia cells transplanted into mice.
1MPA also has an inhibitory effect on the production of tumor necrosis factor (TNF) by murine macrophages activated by tumor cells or lipopolysaccharides.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 170.12 g/mol
• Formel: C₆H₆N₂O₄
• Reinheit: Min. 95%