BRD 3308

CAS: 1550053-02-5

Ref. 3D-BB168411

Produktinformation

• Name: BRD 3308
• Synonyme: 4-4-Acetamido-N-(2-amino-4-fluorophenyl)benzamideBRD3308

Beschreibung

Inhibitor of histone deacetylase 3 (HDAC3) with IC50 in nanomolar range. BRD 9908 was shown to preserve the insulin-secreting pancreatic cells in nonobese diabetic mice. BRD 3308 supressed infiltration of mononuclear cells and prevented β-cell death in vivo as well as increased basal insulin secretion in vitro. Studies on HIV infection models showed that HDAC3 inhibition by BRD 3308 disrupts the HIV latency by increasing the gene expression from HIV promoter.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 287.29 g/mol
• Formel: C₁₅H₁₄FN₃O₂
• Reinheit: Min. 95%
• Farbe/Form: Powder
• InChl: InChI=1S/C15H14FN3O2/c1-9(20)18-12-5-2-10(3-6-12)15(21)19-14-7-4-11(16)8-13(14)17/h2-8H,17H2,1H3,(H,18,20)(H,19,21)
• InChI Key: InChIKey=RRJDFENBXIEAPD-UHFFFAOYSA-N
• SMILES: CC(=O)Nc1ccc(C(=O)Nc2ccc(F)cc2N)cc1