Bragsin 2

CAS: 342795-08-8

Ref. 3D-BB168529

Produktinformation

• Name: Bragsin 2
• Synonyme: 6-Methoxy-5-nitro-2-(trifluoromethyl)-4H-1-benzopyran-4-oneBragsin2

Beschreibung

Inhibitor of BRAG2-mediated activation of Arf GTP-ase. In vitro experiments showed that Bragsin2 inhibits the Arf GTP-ase activation that is mediated by a nucleotide exchange factor BRAG2 in a membrane-dependent manner. Bragsin2 interacts with the PH domain of BRAG2 protein as well as membrane, which prevents the activation of lipidated Arf. Bragsin2 affects the trans-Golgi network and was shown to affect the tumour sphere in breast cancer cell lines.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 289.16 g/mol
• Formel: C₁₁H₆F₃NO₅
• Reinheit: Min. 95%
• Farbe/Form: Solid