BT 18

CAS: 924811-53-0

Ref. 3D-BB170419

Produktinformation

• Name: BT 18
• Synonyme: ([4-[5- [(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)sulfonyl]-2- methoxyphenyl]piperazin-1-yl]-[4-fluoro-2-(trifluoromethyl)- ph enyl]methanone)BT18
• Marke: Biosynth
• Beschreibung: Activator of RET signalling cascade and a derivative of a GFL mimetic compound BT 13. Molecular docking calculations and molecular dynamics simulations were performed in GDNF−GFRα1−RetA complex and showed that BT 18 binds to the allosteric site in GFRα1 as well as RetA surface interfacing GFRα1.

Chemische Eigenschaften

• Molekulargewicht: 637.64 g/mol
• Formel: C₃₀H₃₁F₄N₃O₆S
• Reinheit: Min. 95%
• Farbe/Form: Solid