Picrasin B

CAS: 26121-56-2

Ref. 3D-BBA12156

Produktinformation

• Name: Picrasin B
• Synonyme: Picras-12-ene-1,11,16-trione, 2-hydroxy-12-methoxy-, (2α)-, Phenanthro[10,1-bc]pyran-1,5,11(4H)-trione, 3aβ,6aβ,7,7aα,8,9,10,11a,11bα,11c-decahydro-10α-hydroxy-2-methoxy-3,8α,11aβ,11cβ-tetramethyl-, Nigakilactone I, (2α)-2-Hydroxy-12-methoxypicras-12-ene-1,11,16-trione

Beschreibung

Picrasin B is a quassinoid that is extracted from the bark of the Picrasma quassioides tree. It has been shown to have anti-malarial activity in humans and has been used as a component of traditional medicines in Africa. Picrasin B can be demethylated by alkaline hydrolysis to neoquassin, which is a potent cytotoxic agent against cancer cells. The structure of picrasin B is similar to that of other quassinoids, such as quassia and rhynchophylline. These compounds are monoterpenes with a skeleton that consists of six carbons, five hydroxyls, and two methyl groups on two adjacent carbons. The active metabolite of picrasin B is neoquassin, which can be obtained through demethylation or chlorination.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 376.4 g/mol
• Formel: C₂₁H₂₈O₆
• Reinheit: Min. 95%