DMH 1

CAS: 1206711-16-1

Ref. 3D-BD162772

Produktinformation

• Name: DMH 1
• Synonyme: 4-[6-[4-(1-Methylethoxy)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]-quinolineDMH-1
• Marke: Biosynth
• Beschreibung: A specific inhibitor of Bone Morphogenetic Protein (BMP) type 1 receptors ALK2 and ALK3 (IC50 < 0.5 µM). Dorsomorphin analog that exclusively targets the BMP but not VEGF signaling. It is able to inhibit the BMP-induced Smad1/5/8 activation but not the p38/MAP kinase signaling or Activin A-induced Smad2 activation.

Chemische Eigenschaften

• Molekulargewicht: 380.44 g/mol
• Formel: C₂₄H₂₀N₄O
• Reinheit: Min. 95%
• Farbe/Form: Solid
• InChl: InChI=1S/C24H20N4O/c1-16(2)29-19-9-7-17(8-10-19)18-13-26-24-22(14-27-28(24)15-18)20-11-12-25-23-6-4-3-5-21(20)23/h3-16H,1-2H3
• InChI Key: InChIKey=JMIFGARJSWXZSH-UHFFFAOYSA-N
• SMILES: CC(C)Oc1ccc(-c2cnc3c(-c4ccnc5ccccc45)cnn3c2)cc1