Produktinformation
Delgocitinib is a protein gene inhibitor that binds to the polymerase chain reaction (PCR) enzyme and blocks the transcription of mRNA. Delgocitinib has been shown to be effective in animal models for bowel disease, and it has also demonstrated potential as an anti-inflammatory agent. Delgocitinib binds to the catalytic subunit of DNA-dependent RNA polymerase and inhibits transcription. This drug also inhibits x-ray crystal structures of mammalian DNA gyrase and bacterial DNA topoisomerase IV, which are enzymes required for DNA replication. Delgocitinib is being investigated for its potential use in treating interferon alfa-2b resistant cancers, such as renal cell cancer, bladder cancer, and melanoma.
Delgocitinib has been shown to have acute toxicities in animals. These include decreased locomotor activity, weight loss, increased serum creatinine levels, and decreased levels of potassium in blood
Chemische Eigenschaften
Technische Anfrage zu: 3D-BD178539 Delgocitinib
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