LDN 193189 dihydrochloride

CAS: 1435934-00-1

Ref. 3D-BL162781

Produktinformation

• Name: LDN 193189 dihydrochloride
• Synonyme: 4-[6-[4-(1-Piperazinyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]quinoline 2HCl

Beschreibung

Inhibitor of ALK1, ALK2, ALK3 and ALK6 kinases and bone morphogenetic protein (BMP) pathway. LDN 1931189 is a dorsomorphin derivative that inhibits BMP-mediated activation of Smad, Akt and p38 signalling. LDN 193189 promotes differentiation of human pluripotent cells into PAX6+ anterior neural ectoderm. In combination with basic fibroblast growth factor (FGF2), LDN 193189 promotes differentiation of mouse pluripotent stem cells into inner ear sensory epithelium.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 479.4 g/mol
• Formel: C₂₅H₂₂N₆·2HCl
• Reinheit: Min. 95%
• Farbe/Form: Yellow Powder