Tucatinib

CAS: 937263-43-9

Ref. 3D-BT177688

Produktinformation

• Name: Tucatinib
• CAS: 937263-43-9

Beschreibung

Tucatinib is a small molecule that inhibits the ATP-binding cassette transporter ABCG2 and P-glycoprotein (P-gp) to inhibit cancer cell proliferation. It is used for treatment of breast cancer, in vitro assays, solid tumours, and long-term toxicity studies. Tucatinib has been shown to be effective against her2+ breast cancers. However, due to its side effect profile and potential for drug interactions, tucatinib may not be an appropriate treatment for other types of cancer or disease.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 480.52 g/mol
• Formel: C₂₆H₂₄N₈O₂
• Reinheit: Min. 95%
• InChl: InChI=1S/C26H24N8O2/c1-16-10-17(5-7-22(16)36-19-8-9-34-23(12-19)28-15-30-34)31-24-20-11-18(4-6-21(20)27-14-29-24)32-25-33-26(2,3)13-35-25/h4-12,14-15H,13H2,1-3H3,(H,32,33)(H,27,29,31)
• InChI Key: InChIKey=SDEAXTCZPQIFQM-UHFFFAOYSA-N
• SMILES: Cc1cc(Nc2ncnc3ccc(NC4=NC(C)(C)CO4)cc23)ccc1Oc1ccn2ncnc2c1