URB 597

CAS: 546141-08-6

Ref. 3D-BU140504

Produktinformation

• Name: URB 597
• Synonyme: 3'-Carbamoyl-[1,1'-biphenyl]-3-yl cyclohexylcarbamate, 3′-(Aminocarbonyl)[1,1′-biphenyl]-3-yl N-cyclohexylcarbamate, 3′-Carbamoyl-[1,1′-biphenyl]-3-yl cyclohexylcarbamate, Carbamic acid, N-​ cyclohexyl-​ , 3'-​ (aminocarbonyl)​ [1,​ 1'-​ biphenyl]​ -​ 3-​ yl ester, Carbamic acid, cyclohexyl-, 3′-(aminocarbonyl)[1,1′-biphenyl]-3-yl ester, Kds 4103, Org 231295, Urb 597, Urb597, [3-(3-Carbamoylphenyl)phenyl] N-cyclohexylcarbamate, carbamic acid, N-cyclohexyl-, 3'-(aminocarbonyl)[1,1'-biphenyl]-3-yl ester
• CAS: 546141-08-6

Beschreibung

A selective and potent inhibitor of fatty-acid amide hydrolase, with IC50 values of 5 nM and 3 nM in rat brain and human liver respectively. Anti-inflammatory and anti-hypertensive effects demonstrated in rat models of hypertension. Activation of cannabinoid receptors by URB 596 in inflammatory pain model results in anti-allodynic and anti-hyperalgesic activity.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 338.4 g/mol
• Formel: C₂₀H₂₂N₂O₃
• Reinheit: Min. 95%
• Farbe/Form: Powder
• InChl: InChI=1S/C20H22N2O3/c21-19(23)16-8-4-6-14(12-16)15-7-5-11-18(13-15)25-20(24)22-17-9-2-1-3-10-17/h4-8,11-13,17H,1-3,9-10H2,(H2,21,23)(H,22,24)
• InChI Key: InChIKey=ROFVXGGUISEHAM-UHFFFAOYSA-N
• SMILES: NC(=O)c1cccc(-c2cccc(OC(=O)NC3CCCCC3)c2)c1